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產(chǎn)品名稱: Margatoxin (0.1mg vial)
產(chǎn)品型號: PAR-4290-s
產(chǎn)品展商: 其他品牌
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簡單介紹
Margatoxin (0.1mg vial)
Margatoxin (0.1mg vial)
的詳細(xì)介紹
- Product Code: PAR-4290-s
- Synonyms/Product Alternate Names: Thr-Ile-Ile-Asn-Val-Lys-Cys-Thr-Ser-Pro-Lys-Gln-Cys-Leu-Pro-Pro-Cys-Lys-Ala-Gln-Phe-Gly-Gln-Ser-Ala-Gly-Ala-Lys-Cys-Met-Asn-Gly-Lys-Cys-Lys-Cys-Tyr-Pro-His
- Volgate-Dependent K+ Channel Blocker (Specific for Kv13 Channel)
- Origin: (Scorpion, Centruroides margaritatus)
- Storage Conditions: -20 °C
- Molecular Weight: 4178.9
- Molecular Formula: C178H286N52O50S7
- Disulfide Bonds: (Disulfide bonds between Cys7-Cys29, Cys13-Cys34, and Cys17-Cys36)
- CAS Number: 145808-47-5
- One-Letter Code:
H-TIINVKCTSPKQCLPPCKAQFGQSAGAKCMNGKCKCYPH-OH
R.J. Leonard, M.L. Garcia, R.S. Slaughter, and J.P. Reuben, Proc. Natl. Acad. Sci. U.S.A., 89, 10094 (1992). (Pharmacol.)
M. Garcia-Calvo, R.J. Leonard, J. Novick, S.P. Stevens, W. Schmalhofer, G.J. Kaczorowski, and M.L. Garcia, J. Biol. Chem., 268, 18866 (1993). (Original)
M.A. Bednarek, R.M. Bugianesti, R.J. Leonard, and J.P. Felix, Biochem. Biophys. Res. Commun., 198, 619 (1994). (Chem. Synthesis & S-S Bond)
H.G. Knaus, R.O.A. Koch, A. Eberhart, G.J. Kaczorowski, M.L. Garcia, and R.S. Slaughter, Biochemistry, 34,13627 (1995). (Pharmacol.)