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產(chǎn)品名稱: ProTx-II (0.1mg vial)
產(chǎn)品型號(hào): PTX-4450-s
產(chǎn)品展商: 其他品牌
產(chǎn)品文檔: 無(wú)相關(guān)文檔
簡(jiǎn)單介紹
ProTx-II (0.1mg vial)
ProTx-II (0.1mg vial)
的詳細(xì)介紹
- Product Code: PTX-4450-s
- Synonyms/Product Alternate Names: Tyr-Cys-Gln-Lys-Trp-Met-Trp-Thr-Cys-Asp-Ser-Glu-Arg-Lys-Cys-Cys-Glu-Gly-Met-Val-Cys-Arg-Leu-Trp-Cys-Lys-Lys-Lys-Leu-Trp; ProTx2, ProTx-2
- Na+ Channel (Especially Nav1.7) / Ca2+ Ion Channel Blocker (Gating Modifier)
A tarantula venom-peptide whose sequence is derived from Thrixopelma pruriens.
- Storage Conditions: -20 °C
- Molecular Weight: 3826.6
- Molecular Formula: C168H250N46O41S8
- Disulfide Bonds: (Disulfide Bonds between Cys2- Cys16, Cys9- Cys21, and Cys15- Cys25)
- One-Letter Code:
YCQKWMWTCDSERKCCEGMVCRLWCKKKLW
R.E. Middleton, V.A. Warren, R.L. Kraus, J.C. Hwang, C.J. Liu, G. Dai, R.M. Brochu, M.G. Kohler, Y.-D. Gao, V.M. Garsky, M.J. Bogusky, J.T. Mehl, C.J. Cohen, and M.M. Smith, Biochemistry, 41,14734 (2002).(Original)
J.J. Smith, T.R. Cummins, S. Alphy, and K.M. Blumenthal, J. Biol. Chem., 282, 12687 (2007). (Pharmacol.; Novel Toxin Coupled to NaV Activation)
B.T. Priest, K.M. Blumenthal, J.J. Smith, V.A. Warren, and M.M. Smith, Toxicon, 49,194 (2007). (Review)