The bioactivity was measured by HMEC cell line, PEX can inhibit the transmembrane activity of HMEC under the stimulation of VEGF. MHC class I polypeptide-related sequence A, MIC-A, MICA, PERB11.1, HLA-B, AS, HLAB, HLAC, SPDA1, HLA-B73, HLA-B-7301. C-terminal hemopexin-like domain of MMP-2, PEX. Other PEX Human Recombinant is expressed as inclusion bodies in E.coli having a molecular mass of 28,453 Dalton and subsequently refolded in vitro to get biological activity. The protein was lyophilized with 2mM Tris pH-7.4.