Product Name
6-Phosphogluconolactonase (PGLS), Recombinant Protein
Full Product Name
Recombinant Human 6-Phosphogluconolactonase
Product Synonym Names
PGLS Human; 6-Phosphogluconolactonase Human Recombinant; 6PGL; 6-Phosphogluconolactonase
Product Gene Name
PGLS recombinant protein
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
MGSSHHH HHH SSGLVPRGSH MAAPAP GLIS VFSSSQELGA ALAQLVAQRA ACCLAGARAR FALGLSGGSL VSMLARELPA AVAPAGPASL ARWTLGFCDE RLVPFDHAES TYGLYRTHLL SRLPIPESQV ITINPELPVE EAAEDYAKKL RQAFQGDSIP VFDLLILGVG PDGHTCSLFP DHPLLQEREK IVAPISDSPK PPPQRVTLTL PVLNAARTVI FVATGEGKAA VLKRILEDQE ENPLPAALVQ PHTGKLCWFL DEAAARLLTV PFEKHSTL
3D Structure
ModBase 3D Structure for O95336
Purity/Purification
Greater than 95% as determined by SDS-PAGE.
Form/Format
The PGLS protein solution (1mg/1ml) is formulated in 20mM Tris-HCl buffer (pH 8.0) 1mM DTT, 100mM NaCl and 10% glycerol.
Sterile Filtered clear solution.
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time.Please avoid freeze thaw cycles.
Other Notes
Small volumes of PGLS recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
PGLS recombinant protein
Description: PGLS produced in E Coli is a single, non-glycosylated polypeptide chain containing 278 amino acids (1-258a.a.) and having a molecular mass of 29.7kDa.PGLS is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Introduction: PGLS is an enzyme in the second step pentose phosphate pathway. 6-Phosphogluconolactonase is crucial for the synthesis of nucleotide sugars and NADPH, the key cause for decreasing power. PGLS transforms 6-phosphogluconolactone to 6-phosphogluconate.
Product Categories/Family for PGLS recombinant protein
ENZYMES; Enzymes
NCBI/Uniprot data below describe general gene information for PGLS. It may not necessarily be applicable to this product.
NCBI Accession #
NP_036220.1
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NCBI GenBank Nucleotide #
NM_012088.2
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UniProt Primary Accession #
O95336
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UniProt Related Accession #
O95336[Other Products]
Molecular Weight
27,547 Da
NCBI Official Full Name
6-phosphogluconolactonase
NCBI Official Synonym Full Names
6-phosphogluconolactonase
NCBI Official Symbol
PGLS??[Similar Products]
NCBI Official Synonym Symbols
6PGL
??[Similar Products]
NCBI Protein Information
6-phosphogluconolactonase
UniProt Protein Name
6-phosphogluconolactonase
Protein Family
6-phosphogluconolactonase
UniProt Gene Name
PGLS??[Similar Products]
UniProt Synonym Gene Names
6PGL??[Similar Products]
UniProt Entry Name
6PGL_HUMAN
UniProt Comments for PGLS
PGLS: Hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate. Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.
Protein type: Hydrolase; Carbohydrate Metabolism - pentose phosphate pathway; EC 3.1.1.31
Chromosomal Location of Human Ortholog: 19p13.2
Cellular Component: cytosol
Molecular Function: monosaccharide binding; 6-phosphogluconolactonase activity
Biological Process: pentose-phosphate shunt; pentose-phosphate shunt, oxidative branch; carbohydrate metabolic process; pathogenesis
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
