Product Name
Acid Sphingomyelinase (ASM), Antibody Pair Kit
Full Product Name
Acid Sphingomyelinase (ASM) Antibody Pair Kit (with Standard)
Product Synonym Names
SMPD1; NPD; SMase; aSMase; Sphingomyelin Phosphodiesterase 1,Acid Lysosomal; Simply Sphingomyelinase
Product Gene Name
ASM antibody pair kit
[Similar Products]
Matching Pairs
Antibody: Acid Sphingomyelinase (ASM) (MBS2100260)
Pairing: Acid Sphingomyelinase (ASM) (MBS2100260)
Comments: Matched antibody pair kit containing antibody/standard combination
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
Request Current Manual
Samples
Serum, Plasma, Tissue Homogenates and Other Biological Fluids
Detection Range
0.312-20ng/mL
Standard
Recombinant ASM (Lyophilized, 1 vial-10ug)
Capture Antibody
Rabbit polyclonal antibody (Liquid, 1 vial-400mug/800muL)
Detection Antibody
Biotinylated Rabbit polyclonal antibody (Liquid, 1 vial-100mug/500muL)
Producte Usage
Raw materials can be used for preparation of 5x96T or 10x96T ELISA Kits.
Antibody Support Pack
Antibody Support Pack (Buffer Pack) is sold separately as catalog #MBS2090685
ISO Certification
Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.
Supply Chain Verification
Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customera??s specifications, please inquire.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of ASM antibody pair kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for ASM antibody pair kit
Enzyme & Kinase; Metabolic pathway; Neuro science
Applications Tested/Suitable for ASM antibody pair kit
ELISA (EIA), Chemiluminescence Immunoassays (CLIA), ELISPOT, Luminex
NCBI/Uniprot data below describe general gene information for ASM. It may not necessarily be applicable to this product.
NCBI Accession #
AAA58377.1
[Other Products]
UniProt Secondary Accession #
P17406; Q13811; Q16837; Q16841; A8K8M3; E9PKS3[Other Products]
UniProt Related Accession #
P17405[Other Products]
Molecular Weight
69,624 Da
NCBI Official Full Name
acid sphingomyelinase
NCBI Official Synonym Full Names
sphingomyelin phosphodiesterase 1
NCBI Official Symbol
SMPD1??[Similar Products]
NCBI Official Synonym Symbols
ASM; NPD; ASMASE
??[Similar Products]
NCBI Protein Information
sphingomyelin phosphodiesterase
UniProt Protein Name
Sphingomyelin phosphodiesterase
UniProt Synonym Protein Names
Acid sphingomyelinase
UniProt Gene Name
SMPD1??[Similar Products]
UniProt Synonym Gene Names
ASM; aSMase??[Similar Products]
NCBI Summary for ASM
The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB). Multiple transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2010]
UniProt Comments for ASM
Converts sphingomyelin to ceramide (PubMed:1840600, PubMed:18815062, PubMed:27659707, PubMed:25920558). Also has phospholipase C activities toward 1,2-diacylglycerolphosphocholine and 1,2-diacylglycerolphosphoglycerol.
Research Articles on ASM
1. Parkinson's disease is associated with mutations in SMPD1 gene in Ashkenazi Jews.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.