Cyb5r3; cytochrome b5 reductase 3; 0610016L08Rik; 2500002N19Rik; C85115; Dia-1; Dia1; WU: AL591952.1-001; WU: AL591952.1-002; WU: AL591952.1-003; WU: Cyb5r3; NADH-cytochrome b5 reductase; diaphorase 1; diaphorase 1 (NADH); Dia 1; CYB5R3 / Dia 1 (mouse)

For Research Use Only. Not for use in diagnostic procedures.

100ug of dried peptide

Shipped at ambient temperature, store at -20 degree C

Manufactured in an ISO 9001:2008 Certified Laboratory.

Small volumes of CYB5R3 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

31,550 Da

cytochrome b5 reductase 3

NADH-cytochrome b5 reductase 3

NADH-cytochrome b5 reductase 3

Dia1; B5R; Cytochrome b5 reductase??[Similar Products]

NB5R3_MOUSE

CYB5R3: Desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction. Defects in CYB5R3 are the cause of methemoglobinemia CYB5R3-related (METHB-CYB5R3). A form of methemoglobinemia, a hematologic disease characterized by the presence of excessive amounts of methemoglobin in blood cells, resulting in decreased oxygen carrying capacity of the blood, cyanosis and hypoxia. There are two types of methemoglobinemia CYB5R3-related. In type 1, the defect affects the soluble form of the enzyme, is restricted to red blood cells, and causes well- tolerated methemoglobinemia. In type 2, the defect affects both the soluble and microsomal forms of the enzyme and is thus generalized, affecting red cells, leukocytes and all body tissues. Type 2 methemoglobinemia is associated with mental deficiency and other neurologic symptoms. Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. 3 isoforms of the human protein are produced by alternative promoter.

Protein type: EC 1.6.2.2; Mitochondrial; Carbohydrate Metabolism - amino sugar and nucleotide sugar; Oxidoreductase

Cellular Component: cytoplasm; endoplasmic reticulum; endoplasmic reticulum membrane; membrane; mitochondrial inner membrane; mitochondrial outer membrane; mitochondrion

Molecular Function: ADP binding; AMP binding; cytochrome-b5 reductase activity; FAD binding; NAD binding; oxidoreductase activity; protein binding

Biological Process: cholesterol biosynthetic process; cholesterol metabolic process; lipid metabolic process; steroid biosynthetic process; steroid metabolic process; sterol biosynthetic process

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