Full Product Name
TAS2R38 Antibody
Product Gene Name
anti-TAS2R38 antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P59533
Other Notes
Small volumes of anti-TAS2R38 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Western Blot (WB) of anti-TAS2R38 antibody
Western blot analysis TAS2R38 using COLO205 whole cell lysates
NCBI/Uniprot data below describe general gene information for TAS2R38. It may not necessarily be applicable to this product.
NCBI Accession #
NP_789787.4
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NCBI GenBank Nucleotide #
NM_176817.4
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UniProt Primary Accession #
P59533
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UniProt Secondary Accession #
P59552; Q2M3E8; Q645W3; Q86UK3; A4D1U6[Other Products]
UniProt Related Accession #
P59533[Other Products]
Molecular Weight
37,892 Da
NCBI Official Full Name
taste receptor type 2 member 38
NCBI Official Synonym Full Names
taste 2 receptor member 38
NCBI Official Symbol
TAS2R38??[Similar Products]
NCBI Official Synonym Symbols
PTC; T2R38; T2R61
??[Similar Products]
NCBI Protein Information
taste receptor type 2 member 38
UniProt Protein Name
Taste receptor type 2 member 38
UniProt Synonym Protein Names
PTC bitter taste receptor; Taste receptor type 2 member 61; T2R61
Protein Family
Taste receptor
UniProt Gene Name
TAS2R38??[Similar Products]
UniProt Synonym Gene Names
PTC; T2R38; T2R61??[Similar Products]
NCBI Summary for TAS2R38
This gene encodes a seven-transmembrane G protein-coupled receptor that controls the ability to taste glucosinolates, a family of bitter-tasting compounds found in plants of the Brassica sp. Synthetic compounds phenylthiocarbamide (PTC) and 6-n-propylthiouracil (PROP) have been identified as ligands for this receptor and have been used to test the genetic diversity of this gene. Although several allelic forms of this gene have been identified worldwide, there are two predominant common forms (taster and non-taster) found outside of Africa. These alleles differ at three nucleotide positions resulting in amino acid changes in the protein (A49P, A262V, and V296I) with the amino acid combination PAV identifying the taster variant (and AVI identifying the non-taster variant). [provided by RefSeq, Oct 2009]
UniProt Comments for TAS2R38
Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 ().
Research Articles on TAS2R38
1. this study demonstrated that a Bacillus cereus product(s) elicited an NO-mediated innate defense response in upper airway epithelium that seemed to be partially mediated by a T2R signaling pathway
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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