Taste receptor type 2 member 38; T2R38; PTC bitter taste receptor; Taste receptor type 2 member 61; T2R61; TAS2R38; PTC

For Research Use Only. Not for use in diagnostic procedures.

Store at 4 degree C

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Small volumes of TAS2R38 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9426808 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Taste receptor type 2 member 38 (TAS2R38) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing TAS2R38. The ELISA analytical biochemical technique of the MBS9426808 kit is based on TAS2R38 antibody-TAS2R38 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect TAS2R38 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, TAS2R38. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

37,892 Da

taste 2 receptor member 38

taste receptor type 2 member 38

Taste receptor type 2 member 38

PTC; T2R38; T2R61??[Similar Products]

This gene encodes a seven-transmembrane G protein-coupled receptor that controls the ability to taste glucosinolates, a family of bitter-tasting compounds found in plants of the Brassica sp. Synthetic compounds phenylthiocarbamide (PTC) and 6-n-propylthiouracil (PROP) have been identified as ligands for this receptor and have been used to test the genetic diversity of this gene. Although several allelic forms of this gene have been identified worldwide, there are two predominant common forms (taster and non-taster) found outside of Africa. These alleles differ at three nucleotide positions resulting in amino acid changes in the protein (A49P, A262V, and V296I) with the amino acid combination PAV identifying the taster variant (and AVI identifying the non-taster variant). [provided by RefSeq, Oct 2009]

TAS2R38: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. Belongs to the G-protein coupled receptor T2R family.

Protein type: GPCR, T2R family; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 7q34

Cellular Component: integral to membrane; plasma membrane

Molecular Function: bitter taste receptor activity

Biological Process: detection of chemical stimulus involved in sensory perception of bitter taste

Disease: Thiourea Tasting

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