Anti -ALDH1L1, CT (Aldehyde Dehydrogenase Family 1 Member L1, 10-formyltetrahydrofolate Dehydrogenase, 10-FTHFDH, FTHFD)

For Research Use Only. Not for use in diagnostic procedures.

Chromosome: 3; NC_000003.11 (125822408..125899485, complement). Location: 3q21.3

Polyclonal

IgG

Rabbit

Recognizes human ALDH1L1. Species Crossreactivity: mouse

Purified
Purified by ammonium sulfate precipitation.

Supplied as a liquid in PBS, 0.09% sodium azide.

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Small volumes of anti-ALDH1L1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

ALDH1L1 catalyzes the conversion of 10-formyltetrahydrofolate, NADP, and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family and is responsible for formate oxidation in vivo. Deficiencies in this gene can result in an accumulation of formate and subsequent methanol poisoning.

Antibodies; Abs to Enzymes, Dehydrogenase

ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)

Suitable for use in ELISA, Western Blot, and Immunohistochemistry.
Dilution: ELISA: 1:1000
Western Blot: 1:50-1:100
Immunohistochemistry: 1:50-1:100

98,829 Da[Similar Products]

aldehyde dehydrogenase 1 family, member L1

aldehyde dehydrogenase family 1 member L1; 10-FTHFDH; OTTHUMP00000155221; OTTHUMP00000214696; OTTHUMP00000214700; OTTHUMP00000222724; formyltetrahydrofolate dehydrogenase; 10-formyltetrahydrofolate dehydrogenase; cytosolic 10-formyltetrahydrofolate dehydrogenase

Aldehyde dehydrogenase family 1 member L1

FTHFD??[Similar Products]

AL1L1_HUMAN

The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, NADP, and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family and is responsible for formate oxidation in vivo. Deficiencies in this gene can result in an accumulation of formate and subsequent methanol poisoning. [provided by RefSeq]

ALDH1L1: 2 isoforms of the human protein are produced by alternative splicing

Protein type: Oxidoreductase; Cofactor and Vitamin Metabolism - one carbon pool by folate; EC 1.5.1.6

Chromosomal Location of Human Ortholog: 3q21.3

Cellular Component: mitochondrion

Molecular Function: methyltransferase activity; aldehyde dehydrogenase (NAD) activity; hydroxymethyl-, formyl- and related transferase activity; formyltetrahydrofolate dehydrogenase activity; catalytic activity

Biological Process: methylation; biosynthetic process; one-carbon compound metabolic process; 10-formyltetrahydrofolate catabolic process

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