Muscle, skeletal receptor tyrosine protein kinase; Muscle-specific tyrosine protein kinase receptor; MuSK; Muscle-specific kinase receptor; MUSK; 2.7.10.1

For Research Use Only. Not for use in diagnostic procedures.

For long term storage, please store the entire kit at -20 degree C.

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Small volumes of MUSK elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS2884654 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Muscle, skeletal receptor tyrosine protein kinase (MUSK) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing MUSK. The ELISA analytical biochemical technique of the MBS2884654 kit is based on MUSK antibody-MUSK antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect MUSK antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, MUSK. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

105,589 Da

muscle, skeletal, receptor tyrosine kinase

muscle, skeletal receptor tyrosine protein kinase

Muscle, skeletal receptor tyrosine protein kinase

MuSK; Muscle-specific kinase receptor??[Similar Products]

MUSK_CHICK

Receptor tyrosine kinase which plays a central role in the formation and the maintenance of the neuromuscular junction (NMJ), the synapse between the motor neuron and the skeletal muscle. Recruitment of AGRIN by LRP4 to the MUSK signaling complex induces phosphorylation and activation of MUSK, the kinase of the complex. The activation of MUSK in myotubes regulates the formation of NMJs through the regulation of different processes including the specific expression of genes in subsynaptic nuclei, the reorganization of the actin cytoskeleton and the clustering of the acetylcholine receptors (AChR) in the postsynaptic membrane. May also play a role within the central nervous system by mediating cholinergic responses, synaptic plasticity and memory formation ().

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