1-acylglycerol-3-phosphate O-acyltransferase 1; 1-AGP acyltransferase 1; 1-AGPAT 1; Lysophosphatidic acid acyltransferase alpha; LPAAT-alpha; Protein G15; AGPAT1; G15

For Research Use Only. Not for use in diagnostic procedures.

Polyclonal

IgG

Rabbit

Antigen Affinity Purified

Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.

Small volumes of anti-AGPAT1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone.

ELISA (EIA), Immunohistochemistry (IHC)

Recommended dilution: IHC:1:20-1:200

Immunohistochemistry of paraffin-embedded human kidney using MBS1499462 at dilution 1:100

Immunohistochemistry of paraffin-embedded human placenta using MBS1499462 at dilution 1:100

31,717 Da

1-acylglycerol-3-phosphate O-acyltransferase 1

1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

G15; 1-AGP acyltransferase 1; 1-AGPAT 1; LPAAT-alpha??[Similar Products]

PLCA_HUMAN

This gene encodes an enzyme that converts lysophosphatidic acid (LPA) into phosphatidic acid (PA). LPA and PA are two phospholipids involved in signal transduction and in lipid biosynthesis in cells. This enzyme localizes to the endoplasmic reticulum. This gene is located in the class III region of the human major histocompatibility complex. Alternative splicing results in two transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]

AGPAT1: Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.

Protein type: Membrane protein, multi-pass; Lipid Metabolism - glycerolipid; Lipid Metabolism - glycerophospholipid; EC 2.3.1.51; Membrane protein, integral; Lipid Metabolism - ether lipid; Transferase

Chromosomal Location of Human Ortholog: 6p21.3

Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; membrane

Molecular Function: 1-acylglycerol-3-phosphate O-acyltransferase activity; protein binding

Biological Process: CDP-diacylglycerol biosynthetic process; cellular lipid metabolic process; energy reserve metabolic process; glycerophospholipid biosynthetic process; phosphatidic acid biosynthetic process; phospholipid metabolic process; positive regulation of cellular metabolic process; positive regulation of cytokine and chemokine mediated signaling pathway; positive regulation of cytokine production; triacylglycerol biosynthetic process

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