Product Name
Aspartate aminotransferase, mitochondrial (GOT2), Recombinant Protein
Full Product Name
Recombinant Pig Aspartate aminotransferase, mitochondrial (GOT2)
Product Gene Name
GOT2 recombinant protein
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
30-430aa, Full Length of Mature Protein
Sequence
SSWWAHVEMG PPDPILGVTE AFKRDTNSKK MNLGVGAYRD DNGKPYVLPS VRKAEAQIAA KNLDKEYLPI GGLAEFCKAS AELALGENNE VLKSGRYVTV QTISGTGALR IGANFLQRFF KFSRDVFLPK PSWGNHTPIF RDAGMQLHSY RYYDPKTCGF DFTGALEDIS KIPAQSVILL HACAHNPTGV DPRPEQWKEM ATLVKKNNLF AFFDMAYQGF ASGDGNKDAW AVRHFIEQGI NVCLCQSYAK NMGLYGERVG AFTVVCKDAE EAKRVESQLK ILIRPMYSNP PVNGARIAST ILTSPDLRQQ WLQEVKGMAD RIISMRTQLV SNLKKEGSSH NWQHIVDQIG MFCFTGIKPE QVERLTKEFS IYMTKDGRIS VAGVTSGNVG YLAHAIHQVT K
3D Structure
ModBase 3D Structure for P00506
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of GOT2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
GOT2 recombinant protein
Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology.
NCBI/Uniprot data below describe general gene information for GOT2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_999093.1
[Other Products]
NCBI GenBank Nucleotide #
NM_213928.1
[Other Products]
UniProt Primary Accession #
P00506
[Other Products]
UniProt Secondary Accession #
Q29230[Other Products]
UniProt Related Accession #
P00506[Other Products]
Molecular Weight
47,436 Da
NCBI Official Full Name
aspartate aminotransferase, mitochondrial
NCBI Official Symbol
GOT2??[Similar Products]
NCBI Protein Information
aspartate aminotransferase, mitochondrial
UniProt Protein Name
Aspartate aminotransferase, mitochondrial
UniProt Synonym Protein Names
Fatty acid-binding protein; FABP-1; Glutamate oxaloacetate transaminase 2; Kynurenine aminotransferase 4; Kynurenine aminotransferase IV; Kynurenine--oxoglutarate transaminase 4; Kynurenine--oxoglutarate transaminase IV; Plasma membrane-associated fatty acid-binding protein; FABPpm; Transaminase A
UniProt Gene Name
GOT2??[Similar Products]
UniProt Synonym Gene Names
mAspAT; FABP-1; FABPpm??[Similar Products]
UniProt Comments for GOT2
Catalyzes the irreversible transamination of the L-tryptophan metabolite L-kynurenine to form kynurenic acid (KA). Plays a key role in amino acid metabolism. Important for metabolite exchange between mitochondria and cytosol. Facilitates cellular uptake of long-chain free fatty acids ().
Research Articles on GOT2
1. Thermal aggregation of aspartate aminotransferase from pig heart mitochondria (mAAT) has been studied at various temperatures and various protein concentrations by dynamic light scattering.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
