Product Name
A Cyclase V/VI (Adcy5), Polyclonal Antibody
Popular Item
Full Product Name
A Cyclase V/VI Polyclonal Antibody
Product Synonym Names
ADCY5; Adenylate cyclase type 5; ATP pyrophosphate-lyase 5; Adenylate cyclase type V; Adenylyl cyclase 5; ADCY6; KIAA0422; Adenylate cyclase type 6; ATP pyrophosphate-lyase 6; Adenylate cyclase type VI; Adenylyl cyclase 6; Ca(2+)-inhibitabl
Product Gene Name
anti-Adcy5 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen Affinity Purified
Concentration
1 mg/ml (lot specific)
Immunogen
Synthesized peptide derived from the C-terminal region of human A Cyclase V/VI.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-Adcy5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-Adcy5 antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)
Application Notes for anti-Adcy5 antibody
WB: 1:500-1:2000, IHC: 1:50-1:200, IF: 1:50-1:100, ELISA: 1:5000-1:20000
Western Blot (WB) of anti-Adcy5 antibody
Western Blot analysis of COLO205 cells with A Cyclase V/VI Polyclonal Antibody.
NCBI/Uniprot data below describe general gene information for Adcy5. It may not necessarily be applicable to this product.
NCBI Accession #
NP_072122.1
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NCBI GenBank Nucleotide #
NM_022600.1
[Other Products]
UniProt Related Accession #
Q04400[Other Products]
Molecular Weight
Calculated MW: 139
Observed MW: 138[Observed+MW:+138" title="Find similar products with Calculated MW: 139
Observed MW: 138">Similar Products]
NCBI Official Full Name
adenylate cyclase type 5
NCBI Official Synonym Full Names
adenylate cyclase 5
NCBI Official Symbol
Adcy5??[Similar Products]
NCBI Protein Information
adenylate cyclase type 5
UniProt Protein Name
Adenylate cyclase type 5
UniProt Synonym Protein Names
ATP pyrophosphate-lyase 5; Adenylate cyclase type V; Adenylyl cyclase 5
Protein Family
Adenylate cyclase
UniProt Gene Name
Adcy5??[Similar Products]
UniProt Entry Name
ADCY5_RAT
NCBI Summary for Adcy5
enzyme that catalyzes the formation of the secondary messenger cyclic adenosine monophosphate [RGD, Feb 2006]
UniProt Comments for Adcy5
Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling (PubMed:1409703). Mediates signaling downstream of ADRB1. Regulates the increase of free cytosolic Ca2+ in response to increased blood glucose levels and contributes to the regulation of Ca2+-dependent insulin secretion.
Research Articles on Adcy5
1. Increased expression of adenylyl cyclases V and VI is a major determinant of increased GABAergic transmission in the substantia nigra pars reticulata of animals in which L-DOPA induces severe dyskinesia.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
