Full Product Name
Meis1 Antibody
Product Synonym Names
Homeobox protein Meis1; MEIS1
Product Gene Name
anti-Meis1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for O00470
Species Reactivity
Human, Mouse
Specificity
Meis1 antibody detects endogenous levels of Meis1.
Purity/Purification
Purified from rabbit antiserum by affinity-chromatography using immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1 mg/ml (lot specific)
Target Modification
Unmodified/Total
Immunogen
The antiserum was produced against synthesized peptide derived from human Meis1.
Preparation and Storage
Stable at -20 degree C for at least 1 year.
Other Notes
Small volumes of anti-Meis1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-Meis1 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-Meis1 antibody
WB: 1:500~1:1000
ELISA: 1:10000
Western Blot (WB) of anti-Meis1 antibody
Western blot analysis of lysate from Jurkat cells, using Meis1 antibody.
NCBI/Uniprot data below describe general gene information for Meis1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_002389.1
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NCBI GenBank Nucleotide #
NM_002398.2
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UniProt Primary Accession #
O00470
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UniProt Secondary Accession #
A8MV50[Other Products]
UniProt Related Accession #
O00470[Other Products]
NCBI Official Full Name
homeobox protein Meis1
NCBI Official Synonym Full Names
Meis homeobox 1
NCBI Official Symbol
MEIS1??[Similar Products]
NCBI Protein Information
homeobox protein Meis1
UniProt Protein Name
Homeobox protein Meis1
Protein Family
Homeobox protein
UniProt Gene Name
MEIS1??[Similar Products]
NCBI Summary for Meis1
Homeobox genes, of which the most well-characterized category is represented by the HOX genes, play a crucial role in normal development. In addition, several homeoproteins are involved in neoplasia. This gene encodes a homeobox protein belonging to the TALE ('three amino acid loop extension') family of homeodomain-containing proteins. [provided by RefSeq, Jul 2008]
UniProt Comments for Meis1
Acts as a transcriptional regulator of PAX6. Acts as a transcriptional activator of PF4 in complex with PBX1 or PBX2. Required for hematopoiesis, megakaryocyte lineage development and vascular patterning. May function as a cofactor for HOXA7 and HOXA9 in the induction of myeloid leukemias.
Research Articles on Meis1
1. Conclusions MEIS1 variants were associated with an increased risk of RLS in migraine patients. It is possible that an imbalance in iron homeostasis and the dopaminergic system may represent a link between RLS incidence and migraines.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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