Full Product Name
TMC8 Polyclonal Antibody
Product Gene Name
anti-TMC8 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q8IU68
Other Notes
Small volumes of anti-TMC8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for TMC8. It may not necessarily be applicable to this product.
NCBI Accession #
NP_689681.2
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NCBI GenBank Nucleotide #
NM_152468.4
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UniProt Primary Accession #
Q8IU68
[Other Products]
UniProt Secondary Accession #
Q2YDC0; Q8IWU7; Q8N358; Q8NF04[Other Products]
UniProt Related Accession #
Q8IU68[Other Products]
Molecular Weight
56,132 Da
NCBI Official Full Name
transmembrane channel-like protein 8
NCBI Official Synonym Full Names
transmembrane channel like 8
NCBI Official Symbol
TMC8??[Similar Products]
NCBI Official Synonym Symbols
EV2; EVER2; EVIN2
??[Similar Products]
NCBI Protein Information
transmembrane channel-like protein 8
UniProt Protein Name
Transmembrane channel-like protein 8
UniProt Synonym Protein Names
Epidermodysplasia verruciformis protein 2
Protein Family
Transmembrane channel-like protein
UniProt Gene Name
TMC8??[Similar Products]
UniProt Synonym Gene Names
EVER2; EVIN2??[Similar Products]
NCBI Summary for TMC8
Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. This gene encodes a transmembrane channel-like protein with 8 predicted transmembrane domains and 3 leucine zipper motifs. [provided by RefSeq, Jul 2008]
UniProt Comments for TMC8
Probable ion channel.
Research Articles on TMC8
1. The present study did not show any significant association of the EVER1/2 polymorphisms (rs2290907and rs16970849) with cervical cancer.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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