Human Zinc finger protein 469 (ZNF469) ELISA kit; BCS; KIAA1858; ; zinc finger protein 469

For Research Use Only. Not for use in diagnostic procedures.

Store all reagents at 2-8 degree C

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Small volumes of ZNF469 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS9337700 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the zinc finger protein 469 (ZNF469) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing ZNF469. The ELISA analytical biochemical technique of the MBS9337700 kit is based on ZNF469 antibody-ZNF469 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect ZNF469 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, ZNF469. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).

410,202 Da

zinc finger protein 469

zinc finger protein 469

Zinc finger protein 469

KIAA1858??[Similar Products]

ZN469_HUMAN

This gene encodes a zinc-finger protein. Low-percent homology to certain collagens suggests that it may function as a transcription factor or extra-nuclear regulator factor for the synthesis or organization of collagen fibers. Mutations in this gene cause brittle cornea syndrome. [provided by RefSeq, Jul 2008]

ZNF469: May be involved in transcriptional regulation. Defects in ZNF469 are the cause of brittle cornea syndrome type 1 (BCS1). A disorder characterized by extreme corneal thinning resulting in corneal rupture after minor trauma, blue sclerae, keratoconus or keratoglobus, hyperelasticity of the skin, and hypermobility of the joints. It shares some features with, but is much less severe than, the ocular form of Ehlers-Danlos syndrome (EDS6). Belongs to the krueppel C2H2-type zinc-finger protein family.

Protein type: C2H2-type zinc finger protein

Chromosomal Location of Human Ortholog: 16q24

Cellular Component: nucleus

Molecular Function: DNA binding; metal ion binding

Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent

Disease: Brittle Cornea Syndrome 1

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