Product Name
Neurexin-1-beta (NRXN1), Recombinant Protein
Full Product Name
Recombinant Bovine Neurexin-1-beta (NRXN1), partial
Product Gene Name
NRXN1 recombinant protein
[Similar Products]
Product Synonym Gene Name
NRXN1[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
46-391
Sequence
ASSLG AHHIHHFHGS SKHHSVPIAI YRSPASLRGG HAGTTYIFSK GGGQITYKWP PNDRPSTRAD RLAIGFSTVQ KEAVLVRVDS SSGLGDYLEL HIHQGKIGVK FNVGTDDIAI EESNAIINDG KYHVVRFTRS GGNATLQVDS WPVIERYPAG NNDNERLAIA RQRIPYRLGR VVDEWLLDKG RQLTIFNSQA TIIIGGKEQG QPFQGQLSGL YYNGLKVLNM AAENDANIAI VGNVRLVGEV PSSMTTESTA TAMQSEMSTS IMETTTTLAT STARRGNSPT KEPVSQTTDD ILVASAECPS DDEDIDPCEP SSGGLANPTR AGGREPYPGS AEVIRESSST T
3D Structure
ModBase 3D Structure for Q28142
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of NRXN1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
NRXN1 recombinant protein
Neurexins function in the vertebrate nervous system as cell adhesion molecules and receptors. Two neurexin genes are among the largest known in human (NRXN1 and NRXN3). By using alternate promoters, splice sites and exons, predictions of hundreds or even thousands of distinct mRNAs have been made. Most transcripts use the upstream promoter and encode alpha-neurexin isoforms; fewer transcripts are produced from the downstream promoter and encode beta-neurexin isoforms. Alpha-neurexins contain epidermal growth factor-like (EGF-like) sequences and laminin G domains, and they interact with neurexophilins. Beta-neurexins lack EGF-like sequences and contain fewer laminin G domains than alpha-neurexins. The RefSeq Project has decided to create only a few representative transcript variants of the multitude that are possible.
NCBI/Uniprot data below describe general gene information for NRXN1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001103275.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001109805.2
[Other Products]
UniProt Primary Accession #
Q28142
[Other Products]
UniProt Related Accession #
Q28142; Q28146[Other Products]
Molecular Weight
167,939 Da
NCBI Official Full Name
neurexin-1 isoform 2
NCBI Official Symbol
NRXN1??[Similar Products]
NCBI Protein Information
neurexin-1; neurexin 1
UniProt Protein Name
Neurexin-1-beta
UniProt Synonym Protein Names
Neurexin I-beta
UniProt Gene Name
NRXN1??[Similar Products]
UniProt Comments for NRXN1
Neuronal cell surface protein that may be involved in cell recognition and cell adhesion by forming intracellular junctions through binding to neuroligins. May play a role in formation or maintenance of synaptic junctions. May mediate intracellular signaling. May play a role in angiogenesis ().
Research Articles on NRXN1
1. The crystal structure of the alpha-neurexin-1 extracellular region reveals a hinge point for mediating synaptic adhesion and function
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
