For Research Use Only. Not for use in diagnostic procedures.

Chromosome: 12; NC_000012.11 (43748012..43945724, complement). Location: 12q12

Polyclonal

IgG

Rabbit

The antibody is a rabbit polyclonal antibody raised against ADAM20 conjugated to biotin. It has been selected for its ability to recognize ADAM20 in immunohistochemical staining andwestern blotting.

Affinity Chromatography

Supplied as solution form in PBS, pH7.4, containing 0.02% NaN3,50% glycerol.

200ug/ml (lot specific)

Store at 4 degree C for frequent use. Stored at -20 degree C to -80 degree C in a manual defrost freezer for one year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.

Manufactured in a lab with traceable raw materials. Bulk orders can typically be prepared to the customera??s specifications, please inquire.

Small volumes of anti-ADAM20 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Biotin Antibody

Immunohistochemistry (IHC), ELISA (EIA), Western Blot (WB)

Western blotting: 1:100-400
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200

214,721 Da

ADAM metallopeptidase with thrombospondin type 1 motif, 20

A disintegrin and metalloproteinase with thrombospondin motifs 20; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 20

A disintegrin and metalloproteinase with thrombospondin motifs 20

ADAM-TS 20; ADAM-TS20; ADAMTS-20??[Similar Products]

ATS20_HUMAN

The protein encoded by this gene is a member of the ADAMTS family of zinc-dependent proteases. The encoded protein has a signal peptide that is cleaved to release the mature peptide, which is secreted and found in the extracellular matrix. This protein may be involved in tissue remodeling. [provided by RefSeq, Sep 2011]

ADAMTS20: May play a role in tissue-remodeling process occurring in both normal and pathological conditions. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Apoptosis; EC 3.4.24.-; Secreted; Protease; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 12q12

Cellular Component: extracellular matrix; extracellular space; proteinaceous extracellular matrix

Molecular Function: zinc ion binding; metalloendopeptidase activity

Biological Process: extracellular matrix organization and biogenesis; positive regulation of signal transduction; positive regulation of melanocyte differentiation; proteolysis; negative regulation of apoptosis

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