Anti -HTR3A (5-hydroxytryptamine Receptor 3A, 5-HT3-A, 5-HT3A, 5-hydroxytryptamine Receptor 3, 5-HT-3, 5-HT3R, Serotonin Receptor 3A, Serotonin-gated Ion Channel Receptor, 5HT3R, HTR3)

For Research Use Only. Not for use in diagnostic procedures.

Chromosome: 9; NC_000075.6 (48899213..48911099, complement). Location: 9 A5.3; 9

Polyclonal

Goat

Recognizes HTR3A. Species Crossreactivity: Human and rat.

Affinity Purified
Purified by immunoaffinity chromatography.

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Small volumes of anti-Htr3a antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel.

Antibodies; Abs to Serotonin Receptors

ELISA (EL/EIA), Western Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Suitable for use in ELISA, Immunocytochemistry, Immunofluorescence and Western Blot.
Dilution: ELISA: 1:128,000
Western Blot: 0.3-1ug/ml, observed in human colon lysates on ~55kD bands

56,056 Da[Similar Products]

5-hydroxytryptamine (serotonin) receptor 3A

5-hydroxytryptamine receptor 3A; 5-HT-3; 5-HT3A; 5-HT3R; 5-HT3-A; serotonin receptor 3A; 5HT3 serotonin receptor; serotonin-gated ion channel receptor

5-hydroxytryptamine receptor 3A

5ht3; Htr3; 5-HT3-A; 5-HT3A; 5-HT-3; 5-HT3R??[Similar Products]

5HT3A_MOUSE

5-HT(3): This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel. Belongs to the ligand-gated ion channel (TC 1.A.9) family. 5-hydroxytryptamine receptor (TC 1.A.9.2) subfamily. HTR3A sub-subfamily. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Channel, ligand-gated; Membrane protein, multi-pass; Transporter, ion channel; Channel, cation

Cellular Component: postsynaptic membrane; cell soma; membrane; axon; cytoplasm; integral to membrane; plasma membrane; synapse; cell junction

Molecular Function: serotonin binding; serotonin-activated cation-selective channel activity; voltage-gated potassium channel activity; serotonin receptor activity; ligand-gated ion channel activity; extracellular ligand-gated ion channel activity

Biological Process: transport; ion transport; serotonin receptor signaling pathway; cation transport

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