Product Name
A disintegrin and metalloproteinase with thrombospondin motifs 20 (Adamts20), Recombinant Protein
Full Product Name
Recombinant Mouse A disintegrin and metalloproteinase with thrombospondin motifs 20 (Adamts20) , partial
Product Gene Name
Adamts20 recombinant protein
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P59511
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Adamts20 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for Adamts20. It may not necessarily be applicable to this product.
NCBI Accession #
NP_803180.3
[Other Products]
NCBI GenBank Nucleotide #
NM_177431.5
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UniProt Primary Accession #
P59511
[Other Products]
UniProt Secondary Accession #
E9QLA1[Other Products]
UniProt Related Accession #
P59511[Other Products]
Molecular Weight
158,027 Da
NCBI Official Full Name
A disintegrin and metalloproteinase with thrombospondin motifs 20 isoform 1 preproprotein
NCBI Official Synonym Full Names
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 20
NCBI Official Symbol
Adamts20??[Similar Products]
NCBI Official Synonym Symbols
bt; Adamst20
??[Similar Products]
NCBI Protein Information
A disintegrin and metalloproteinase with thrombospondin motifs 20
UniProt Protein Name
A disintegrin and metalloproteinase with thrombospondin motifs 20
Protein Family
A disintegrin and metalloproteinase with thrombospondin motifs
UniProt Gene Name
Adamts20??[Similar Products]
UniProt Synonym Gene Names
ADAM-TS 20; ADAM-TS20; ADAMTS-20??[Similar Products]
NCBI Summary for Adamts20
This gene encodes a member of "a disintegrin and metalloproteinase with thrombospondin motifs" (ADAMTS) family of multi-domain matrix-associated metalloendopeptidases that have diverse roles in tissue morphogenesis and pathophysiological remodeling, in inflammation and in vascular
biology. The encoded preproprotein undergoes proteolytic processing to generate an active protease. Certain mutations in this gene cause defective development of neural crest-derived melanoblasts resulting in a "belted" phenotype that is characterized by white spots in the lumbar region. [provided by RefSeq, Jul 2016]
UniProt Comments for Adamts20
May play a role in tissue-remodeling process occurring in both normal and pathological conditions. May have a protease-independent function in the transport from the endoplasmic reticulum to the Golgi apparatus of secretory cargos, mediated by the GON domain.
Research Articles on Adamts20
1. These findings support a model in which cooperative versican proteolysis by ADAMTS9 in vascular endothelium and by ADAMTS20 in palate mesenchyme drives palatal shelf sculpting and extension.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
