Product Name
Complement C2, ELISA Kit
Full Product Name
Human Complement C2 ELISA Kit
Product Synonym Names
Complement C2; C3/C5 convertase; C2; 3.4.21.43
Product Gene Name
C2 elisa kit
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
Request Current Manual
3D Structure
ModBase 3D Structure for P06681
Detection Range
15.6-1000 ng/mL
Preparation and Storage
For long term storage, please store the entire kit at -20 degree C.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of C2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for C2 purchase
MBS289915 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Complement C2, ELISA Kit target analytes in
biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing C2. The ELISA analytical biochemical technique of the MBS289915 kit is based on C2 antibody-C2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect C2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, C2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
NCBI/Uniprot data below describe general gene information for C2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000054.2
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NCBI GenBank Nucleotide #
NM_000063.5
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UniProt Primary Accession #
P06681
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UniProt Secondary Accession #
O19694; Q13904; B4DPF3; B4DV20; E9PFN7[Other Products]
UniProt Related Accession #
P06681[Other Products]
Molecular Weight
69,444 Da
NCBI Official Full Name
complement C2 isoform 1 preproprotein
NCBI Official Synonym Full Names
complement component 2
NCBI Official Symbol
C2??[Similar Products]
NCBI Official Synonym Symbols
CO2; ARMD14
??[Similar Products]
NCBI Protein Information
complement C2
UniProt Protein Name
Complement C2
UniProt Synonym Protein Names
C3/C5 convertase
Protein Family
Complement C2
UniProt Gene Name
C2??[Similar Products]
UniProt Entry Name
CO2_HUMAN
NCBI Summary for C2
Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined.[provided by RefSeq, Mar 2009]
UniProt Comments for C2
Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase.
Research Articles on C2
1. our data indicate that C2 rs547154 polymorphism plays a protective role in the development of PCV.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
