Product Name
Tyk 2 Peptide (Tk), Peptide
Full Product Name
Tyk 2 Peptide (Non-receptor Tyrosine Kinase)
Product Gene Name
Tk peptide
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
Chromosome: 3R; NT_033777.2 (7819897..7831155, complement). Location: 87A4-87A4
3D Structure
ModBase 3D Structure for Q9VGE8
Purity/Purification
Purified
~90% by HPLC and MS analysis
Form/Format
Supplied as a lyophilized powder.
Sequence (linear)
Ac-Cys-Val-His-Glu-Lys-Tyr-Gln-Gly-Gln-Ala-Pro-Ser-Val-Phe-Ser-Val-NH2
Amino Acid Analysis
Confirms expected sequence
Preparation and Storage
Lyophilized powder may be stored at 4 degree C for short-term only. Stable for 12 months at -20 degree C. Reconstitute to nominal volume (see reconstitution instructions for peptides) and store at -20 degree C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
Other Notes
Small volumes of Tk peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
Tk peptide
Control peptide for the Tyk 2 rabbit polyclonal antibody
Product Categories/Family for Tk peptide
Molecular Biology; MB-Receptor Tyrosine Kinases
NCBI/Uniprot data below describe general gene information for Tk. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001262493.1
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NCBI GenBank Nucleotide #
NM_001275564.1
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UniProt Primary Accession #
Q9VGE8
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UniProt Secondary Accession #
Q8SZ21; Q9NBJ5; B5RJL9[Other Products]
UniProt Related Accession #
Q9VGE8[Other Products]
Molecular Weight
1819[Similar Products]
NCBI Official Full Name
tachykinin, isoform B
NCBI Official Synonym Full Names
Tachykinin
NCBI Official Symbol
Tk??[Similar Products]
NCBI Official Synonym Symbols
CG14734; DmelCG14734; Drm-TK; Drm-TK-1; Drm-TK-2; Drm-TK-3; Drm-TK-4; Drm-TK-5; Drm-TK-6; dtk; Dtk; DTK; DTK-1; DTK-2; DTK-3; DTK-4; DTK-5; DTK-6; DTK1; TK; TK-1; Tyk
??[Similar Products]
NCBI Protein Information
CG14734 gene product from transcript CG14734-RB; CG14734-PA; CG14734-PB; Tk-PA; Tk-PB; neurokinin; preprotachykinin; tachykinin-1; tachykinin-3; tachykinin-6; tachykinin-like peptide
UniProt Protein Name
Tachykinins
UniProt Synonym Protein Names
dTkCleaved into the following 11 chains:Tachykinin-related peptide 1; TK-1; dTK-1; Alternative name(s):; APTSSFIGMR-amideTachykinin-associated peptide 1; TAP1; Alternative name(s):; DEEHDTSEGNWLGSGPDPLDYADEEADSSYAEN-amideTachykinin-related peptide 2; TK-2; dTK-2; Alternative name(s):; APLAFVGLR-amideTachykinin-associated peptide 2; TAP2; Alternative name(s):; FIPINNRLSDVLQSLEEERLRDSLLQDFFDRVAGRDGSAV-amideTachykinin-related peptide 3; TK-3; dTK-3; Alternative name(s):; APTGFTGMR-amideTachykinin-associated peptide 3; TAP3; Alternative name(s):; Brain peptide PALLAGDDDAEADEATELQQTachykinin-related peptide 4; TK-4; dTK-4; Alternative name(s):; APVNSFVGMR-amideTachykinin-associated peptide 4; TAP4; Alternative name(s):; Brain peptide DVSHQHYTachykinin-associated peptide 5; TAP5; Alternative name(s):; AALSDSYDLRGKQQRFADFNSKFVAVR-amideTachykinin-associated peptide 6; TAP6; Alternative name(s):; Brain peptide SDLEGNGVGIGDDHEQALVHPWLYLWGETachykinin-related peptide 5; TK-5; dTK-5; Alternative name(s):; APNGFLGMR-amide
Protein Family
Thymidine kinase
UniProt Gene Name
Tk??[Similar Products]
UniProt Synonym Gene Names
TK-1; dTK-1; TAP1; TK-2; dTK-2; TAP2; TK-3; dTK-3; TAP3; TK-4; dTK-4; TAP4; TAP5; TAP6; TK-5; dTK-5??[Similar Products]
UniProt Entry Name
TACHY_DROME
UniProt Comments for Tk
Function: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Stimulates gut muscle contractions. Ref.1
Subcellular location: Secreted
Potential.
Tissue specificity: Strong expression is seen in a group of 14 cells plus one isolated cell in the midgut of stage 17 embryos. Also expressed in a pair of medially located unidentified cells, just posterior to the brain, and in two lateral groups of cells that may be associated with tracheae. Expression in the larval gut is restricted to cells with endocrine cell-like morphology in the posterior midgut, just anterior to the malphigian tubules. In the brain, expression is detected in a restricted number of neuronal cell bodies. Expression in the ***** female gut is restricted to the midgut with no expression detected in the hindgut. Ref.1
Sequence similarities: Belongs to the tachykinin family.
Research Articles on Tk
1. The control of DILP5 signaling in the renal tubules by Drosophila tachykinin peptide (DTK) and its receptor DTKR during desiccative, nutritional and oxidative stress, was investigated.
Precautions
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Disclaimer
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