Product Name
cytochrome P450, family 17, subfamily A, polypeptide 1 (CYP17A1), ELISA Kit
Full Product Name
Pig Steroid 17-alpha-hydroxylase/17, 20 lyase, CYP17A1 ELISA Kit
Product Synonym Names
Pig Steroid 17-alpha-hydroxylase/17; 20 lyase (CYP17A1) ELISA kit; RP11-753C18.1; CPT7; CYP17; P450C17; S17AH; cytochrome P450; subfamily XVII (steroid 17-alpha-hydroxylase); adrenal hyperplasia; cytochrome p450 XVIIA1; steroid 17-alpha-hydroxylase/17; 20 lyase; steroi; cytochrome P450; family 17; subfamily A; polypeptide 1
Product Gene Name
CYP17A1 elisa kit
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
Request Current Manual
3D Structure
ModBase 3D Structure for P19100
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of CYP17A1 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for CYP17A1 purchase
MBS9329553 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the cytochrome P450, family 17, subfamily A, polypeptide 1 (CYP17A1) ELISA Kit target analytes in
biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing CYP17A1. The ELISA analytical biochemical technique of the MBS9329553 kit is based on CYP17A1 antibody-CYP17A1 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect CYP17A1 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, CYP17A1. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
NCBI/Uniprot data below describe general gene information for CYP17A1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_999593.1
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NCBI GenBank Nucleotide #
NM_214428.1
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UniProt Primary Accession #
P19100
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UniProt Secondary Accession #
Q29553; Q99030[Other Products]
UniProt Related Accession #
P19100[Other Products]
Molecular Weight
57,447 Da
NCBI Official Full Name
steroid 17-alpha-hydroxylase/17,20 lyase
NCBI Official Symbol
CYP17A1??[Similar Products]
NCBI Official Synonym Symbols
CYP17; P450c17
??[Similar Products]
NCBI Protein Information
steroid 17-alpha-hydroxylase/17,20 lyase; CYPXVII; cytochrome P450c17; cytochrome P450-C17; steroid 17-alpha-monooxygenase; 17-alpha-hydroxylase cytochrome P450; 17-alpha-hydroxyprogesterone aldolase
UniProt Protein Name
Steroid 17-alpha-hydroxylase/17,20 lyase
UniProt Synonym Protein Names
17-alpha-hydroxyprogesterone aldolase; CYPXVII; Cytochrome P450 17A1; Cytochrome P450-C17; Cytochrome P450c17
Protein Family
Steroid 17-alpha-hydroxylase/17,20 lyase
UniProt Gene Name
CYP17A1??[Similar Products]
UniProt Synonym Gene Names
CYP17; Cytochrome P450c17??[Similar Products]
UniProt Entry Name
CP17A_PIG
UniProt Comments for CYP17A1
Function: Conversion of pregnenolone and progesterone to their 17-alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. Involved in sexual development during fetal life and at puberty.
Catalytic activity: A C(21)-steroid + (reduced NADPH--hemoprotein reductase) + O2 = a 17-alpha-hydroxy-C(21)-steroid + (oxidized NADPH--hemoprotein reductase) + H2O.
Cofactor: Heme group
Enzyme regulation: Regulated predominantly by intracellular cAMP levels.
Research Articles on CYP17A1
1. The immunolocalization of P450c17, detected in the ovaries of pregnant pigs and fetal porcine gonads, indicates the potential sites of androgen synthesis.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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