Product Name
Activin receptor type-2B (ACVR2B), Recombinant Protein
Full Product Name
Recombinant Chicken Activin receptor type-2B (ACVR2B), partial
Product Gene Name
ACVR2B recombinant protein
[Similar Products]
Product Synonym Gene Name
ACVR2B[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
25-137
Sequence
ETRECI YYNANWELEK TNQSGVERCE GEKDKRLHCY ASWRNNSGSI ELVKKGCWLD DFNCYDRQEC VATEENPQVF FCCCEGNYCN EKFTHLPEVT GPEVIYEPPP PTPSLLN
3D Structure
ModBase 3D Structure for Q90670
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Gallus gallus (Chicken)
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of ACVR2B recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for ACVR2B. It may not necessarily be applicable to this product.
NCBI Accession #
NP_989648.1
[Other Products]
NCBI GenBank Nucleotide #
NM_204317.1
[Other Products]
UniProt Primary Accession #
Q90670
[Other Products]
UniProt Related Accession #
Q90670[Other Products]
Molecular Weight
57,776 Da
NCBI Official Full Name
activin receptor type-2B
NCBI Official Synonym Full Names
activin A receptor type 2B
NCBI Official Symbol
ACVR2B??[Similar Products]
NCBI Official Synonym Symbols
ActRIIB; ACTR-IIB
??[Similar Products]
NCBI Protein Information
activin receptor type-2B
UniProt Protein Name
Activin receptor type-2B
UniProt Synonym Protein Names
Activin receptor type IIB; ACTR-IIB
Protein Family
Activin receptor
UniProt Gene Name
ACVR2B??[Similar Products]
UniProt Synonym Gene Names
ACTR-IIB??[Similar Products]
UniProt Comments for ACVR2B
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A. May modulate neuropeptide expression in dorsal root ganglia (DRG) neurons and ovarian follicle development.
Research Articles on ACVR2B
1. This study demonstrated that the role of ACVR2B expression in ciliary ganglion neuronal development, investigating its function in neuronal differentiation and ontogenetic cell death.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
