Product Name
(Rhesus macaque) Cathepsin K (CTSK), Recombinant Protein
Popular Item
Full Product Name
Recombinant Macaca mulatta (Rhesus macaque) Cathepsin K (CTSK)
Product Synonym Names
Recombinant (Rhesus macaque) Cathepsin K (CTSK); Cathepsin K EC= 3.4.22.38
Product Gene Name
CTSK recombinant protein
[Similar Products]
Product Synonym Gene Name
CTSK[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
115-329
Sequence
APDSVDYRKK GYVTPVKNQG QCGSCWAFSS VGALEGQLKK KTGKLLNLSP QNLVDCVSEN DGCGGGYMTN AFQYVQKNRG IDSEDAYPYV GQEESCMYNP TGKAAKCRGY REIPEGNEKA LKRAVARVGP VSVAIDASLT SFQFYSKGVY YDESCNSDNL NHAVLAVGYG IQKGNKHWII KNSWGENWGN KGYILMARNK NNACGIANLA SFPKM
Chromosome Location
Chromosome: 1; NC_007858.1 (129200296..129211730, complement). Location: chromosome: 1
3D Structure
ModBase 3D Structure for P61277
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>=90% (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Macaca mulatta (Rhesus macaque)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of CTSK recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for CTSK. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001027984.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001032812.2
[Other Products]
UniProt Primary Accession #
P61277
[Other Products]
UniProt Secondary Accession #
O77641[Other Products]
UniProt Related Accession #
P61277[Other Products]
Molecular Weight
36,942 Da[Similar Products]
NCBI Official Full Name
cathepsin K
NCBI Official Symbol
CTSK??[Similar Products]
NCBI Protein Information
cathepsin K; cathepsin K preproprotein
UniProt Protein Name
Cathepsin K
UniProt Gene Name
CTSK??[Similar Products]
UniProt Entry Name
CATK_MACMU
UniProt Comments for CTSK
Function: Closely involved in osteoclastic bone resorption and may participate partially in the disorder of bone remodeling. Displays potent endoprotease activity against fibrinogen at acid pH. May play an important role in extracellular matrix degradation
By similarity.
Catalytic activity: Broad proteolytic activity. With small-molecule substrates and inhibitors, the major determinant of specificity is P2, which is preferably Leu, Met > Phe, and not Arg.
Subcellular location: Lysosome
By similarity.
Sequence similarities: Belongs to the peptidase C1 family.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
