Full Product Name
GFAP antibody
Product Synonym Names
Mouse monoclonal GFAP antibody; Monoclonal GFAP antibody; Anti-GFAP antibody; Glial marker; Glial Filament Protein antibody; Glial Fibrillary Acid Protein antibody
Product Gene Name
anti-GFAP antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Form/Format
Lyophilized powder
Immunogen
GFAP antibody was raised in mouse using GFAP from pig spinal cord as the immunogen
Preparation and Storage
Store at 4 degree C for short term storage.
For long term storage aliquot and store at-20 degree C.
Avoid repeated freeze/thaw cycles.
Other Notes
Small volumes of anti-GFAP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-GFAP antibody
Glial fibrillary acidic protein (GFAP) is an intermediate filament (IF) protein that was thought to be specific for astrocytes in the central nervous system (CNS). Later, it was shown that GFAP is also expressed by other cell types in CNS, including ependymal cells.
Product Categories/Family for anti-GFAP antibody
Neuroscience
Applications Tested/Suitable for anti-GFAP antibody
Western Blot (WB), Immunohistochemistry (IHC) Formalin/Paraffin
NCBI/Uniprot data below describe general gene information for GFAP. It may not necessarily be applicable to this product.
NCBI Accession #
AAB22581.1
[Other Products]
UniProt Secondary Accession #
Q53H98; Q5D055; Q6ZQS3; Q7Z5J6; Q7Z5J7; Q96KS4; Q96P18; Q9UFD0; B2RD44; D3DX59; E9PAX3[Other Products]
UniProt Related Accession #
P14136[Other Products]
Molecular Weight
49,508 Da
NCBI Official Full Name
glial fibrillary acidic protein
NCBI Official Synonym Full Names
glial fibrillary acidic protein
NCBI Official Symbol
GFAP??[Similar Products]
NCBI Official Synonym Symbols
ALXDRD
??[Similar Products]
NCBI Protein Information
glial fibrillary acidic protein
UniProt Protein Name
Glial fibrillary acidic protein
Protein Family
Glial fibrillary acidic protein
UniProt Gene Name
GFAP??[Similar Products]
UniProt Synonym Gene Names
GFAP??[Similar Products]
NCBI Summary for GFAP
This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]
UniProt Comments for GFAP
GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.
Research Articles on GFAP
1. The authors observed higher serum levels of GFAP and UCH-L1 in brain-injured children compared with controls and also demonstrated a step-wise increase of biomarker concentrations over the continuum of severity from mild to severe traumatic brain injury. Serum UCH-L1 and GFAP concentrations also strongly predicted poor outcome.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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