Product Name
(Rhesus macaque) Interferon-induced GTP-binding protein Mx1 (MX1), Recombinant Protein
Popular Item
Full Product Name
Recombinant Macaca mulatta (Rhesus macaque) Interferon-induced GTP-binding protein Mx1 (MX1)
Product Synonym Names
Recombinant (Rhesus macaque) Interferon-induced GTP-binding protein Mx1 (MX1); Interferon-induced GTP-binding protein Mx1; Myxoma resistance protein 1 Myxovirus resistance protein 1 Cleaved into the following chain: 1. Interferon-induced GTP-binding prote
Product Gene Name
MX1 recombinant protein
[Similar Products]
Product Synonym Gene Name
MX1[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
VLSEVDIVKA DPAAASQPLL LNGDADVAQK SPGSVAENNL CSQYEEKVRP CIDLIDSLRA LGVEQDLALP AIAVIGDQSS GKSSVLEALS GVALPRGSGI VTRCPLVLKL KKLVNEDEWR GKVSYQDYEI EILDASEVEK EINKAQNTIA GEGMGISHEL ITLEISSRDV PDLTLIDLPG ITRVAVGNQP PDIGYKIKTL IRKYIQRQET INLVVVPSNV DIATTEALSM AQEVDPEGDR TIGILTKPDL VDKGTEDKVV DVVRNLVFHL KKGYMIVKCR GQQEIQDQLS LSEALQREKI FFEDHPHFRD LLEEGKATIP CLAEKLTSEL IAHICKSLPL LENQIKESHQ GITEELQKYG VDIPEDENEK MFFLIDKINA FNQDITALIQ GEETVGEDDS RLFTRLRREF HKWGIIIENN LQEGHKITSR KMQKFENQYR GRELPGFVNY RTFETIVKQQ IKALEEPAVN MLHTVTDMVR LAFTDVSMKN FEELFNLHRT AKSKIEDIRT EQEREGEKLI RLHFQMEQIV YCQDQVYRGA LQKVREKELE EEKKKKSWDI GTFQPSSTES SMEEIFQHLM AYHQEASKRI SSHIPLVIQF FMLQMYGQQL QKAMLQLLQD KDTYSWLLKE RSDTSDKRKF LKERLARLTQ ARRRLAQFPG
Chromosome Location
Chromosome: 3; NC_007860.1 (5188157..5216916, complement). Location: chromosome: 3
3D Structure
ModBase 3D Structure for A1E2I4
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>=90% (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Macaca mulatta (Rhesus macaque)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of MX1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for MX1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001073161.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001079693.2
[Other Products]
UniProt Primary Accession #
A1E2I4
[Other Products]
UniProt Related Accession #
A1E2I4[Other Products]
Molecular Weight
75,431 Da[Similar Products]
NCBI Official Full Name
interferon-induced GTP-binding protein Mx1
NCBI Official Symbol
MX1??[Similar Products]
NCBI Protein Information
interferon-induced GTP-binding protein Mx1; myxoma resistance protein 1; myxovirus resistance protein 1
UniProt Protein Name
Interferon-induced GTP-binding protein Mx1
UniProt Synonym Protein Names
Myxoma resistance protein 1; Myxovirus resistance protein 1
Protein Family
Interferon-induced GTP-binding protein
UniProt Gene Name
MX1??[Similar Products]
UniProt Entry Name
MX1_MACMU
UniProt Comments for MX1
Function: Dynamin-like GTPase acting as a cell-autonomous host restriction factor against many viral pathogens
By similarity.May regulate the calcium channel activity of TRPCs. Ring-like assemblies may induce membrane tubulation
By similarity.
Subunit structure: Oligomerizes (via the stalk domain) in a criss-cross pattern to form a linear stalk filament, may form ring-like structures with a 24 Angstrom inner diameter. Interacts with TRPC1, TRPC3, TRPC4, TRPC5, TRPC6 and TRPC7
By similarity.
Subcellular location: Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side
By similarity. Note: Binds preferentially to negatively charged phospholipids
By similarity.
Induction: By type I and type III interferons.
Sequence similarities: Belongs to the dynamin family.Contains 1 GED domain.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
