Product Name
(Rhesus macaque) Interleukin-12 subunit alpha (IL12A), Recombinant Protein
Popular Item
Full Product Name
Recombinant Macaca mulatta (Rhesus macaque) Interleukin-12 subunit alpha (IL12A)
Product Synonym Names
Recombinant (Rhesus macaque) Interleukin-12 subunit alpha (IL12A); Interleukin-12 subunit alpha; IL-12A; Cytotoxic lymphocyte maturation factor 35 kDa subunit; CLMF p35 IL-12 subunit p35
Product Gene Name
IL12A recombinant protein
[Similar Products]
Product Synonym Gene Name
IL12A[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
23-219
Sequence
RNLSVATPGP EMFPCLHHSQ NLLKAASNTL QKARQILEFY PCTSEEIDHE DITKDKTSTV EACLPLELIK NESCLNSRET SFITNGSCLA SRKTSFMMAL CLRSIYEDLK MYQVEFKTMN AKLLRDPKRQ IFLDQNILGV IDELMQALNF NSETVPQKSS LEEPDFYKTK IKLCILLHAF RIRAVTIDRV MSYLNAS
Chromosome Location
Chromosome: 2; NC_007859.1 (127725488..127731994, complement). Location: chromosome: 2
3D Structure
ModBase 3D Structure for P48091
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>=90% (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Macaca mulatta (Rhesus macaque)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of IL12A recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for IL12A. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001038199.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001044734.1
[Other Products]
UniProt Primary Accession #
P48091
[Other Products]
UniProt Related Accession #
P48091[Other Products]
Molecular Weight
24,904 Da[Similar Products]
NCBI Official Full Name
interleukin-12 subunit alpha
NCBI Official Symbol
IL12A??[Similar Products]
NCBI Official Synonym Symbols
IL-12A
??[Similar Products]
NCBI Protein Information
interleukin-12 subunit alpha; CLMF p35; IL-12 subunit p35; cytotoxic lymphocyte maturation factor 35 kDa subunit
UniProt Protein Name
Interleukin-12 subunit alpha
UniProt Synonym Protein Names
Cytotoxic lymphocyte maturation factor 35 kDa subunit; CLMF p35; IL-12 subunit p35
Protein Family
Interleukin
UniProt Gene Name
IL12A??[Similar Products]
UniProt Synonym Gene Names
IL-12A; CLMF p35??[Similar Products]
UniProt Entry Name
IL12A_MACMU
UniProt Comments for IL12A
Function: Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC
By similarity.
Subunit structure: Heterodimer with IL12B; disulfide-linked. The heterodimer is known as interleukin IL-12
By similarity.
Subcellular location: Secreted.
Sequence similarities: Belongs to the IL-6 superfamily.
Sequence caution: The sequence AAA86707.1 differs from that shown. Reason: Erroneous initiation.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
