Product Name
5,7-Dihydroxytryptamine, Conjugated (Htr1a), Polyclonal Antibody
Full Product Name
5,7-Dihydroxytryptamine, Conjugated
Product Synonym Names
Anti -5,7-Dihydroxytryptamine, Conjugated
Product Gene Name
anti-Htr1a antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Chromosome Location
Chromosome: 2; NC_005101.3 (55362662..55363930). Location: 2q16
3D Structure
ModBase 3D Structure for P19327
Specificity
Recognizes protein-linked 5,7-Dihydroxytryptamine.
Purity/Purification
Purified
Purified by protein carrier (BSA) affinity column, and ammonium sulphate precipitation.
Form/Format
Supplied as a lyophilized powder. Reconstitute with 50ul sterile dH2O.
Immunogen
Synthetic 5,7-dihydroxytryptamine conjugated to protein carriers.
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 2 months at 4 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Other Notes
Small volumes of anti-Htr1a antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-Htr1a antibody
Antibodies; Abs to Amino Acids
Application Notes for anti-Htr1a antibody
Other applications not tested.
NCBI/Uniprot data below describe general gene information for Htr1a. It may not necessarily be applicable to this product.
NCBI Accession #
NP_036717.1
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NCBI GenBank Nucleotide #
NM_012585.1
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UniProt Primary Accession #
P19327
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UniProt Related Accession #
P19327[Other Products]
Molecular Weight
46,429 Da[Similar Products]
NCBI Official Full Name
5-hydroxytryptamine receptor 1A
NCBI Official Synonym Full Names
5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
NCBI Official Symbol
Htr1a??[Similar Products]
NCBI Official Synonym Symbols
5HT1A; RAT5HT1A
??[Similar Products]
NCBI Protein Information
5-hydroxytryptamine receptor 1A; 5-HT1A; 5-HT-1A; serotonin receptor 1A
UniProt Protein Name
5-hydroxytryptamine receptor 1A
UniProt Synonym Protein Names
Serotonin receptor 1A
Protein Family
5-hydroxytryptamine receptor
UniProt Gene Name
Htr1a??[Similar Products]
UniProt Synonym Gene Names
5ht1a; 5-HT-1A; 5-HT1A??[Similar Products]
UniProt Entry Name
5HT1A_RAT
NCBI Summary for Htr1a
regulates AMPA receptor channels in the prefrontal cortex; regulation is mediated via inhibition of Ca2+/calmodulin-dependent kinase II [RGD, Feb 2006]
UniProt Comments for Htr1a
5-HT(1A): This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Belongs to the G-protein coupled receptor 1 family. 5- hydroxytryptamine receptor subfamily. HTR1A sub-subfamily.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1
Cellular Component: axon hillock; cell soma; membrane; integral to plasma membrane
Molecular Function: protein binding; serotonin binding; serotonin receptor activity; G-protein alpha-subunit binding; drug binding
Biological Process: G-protein coupled receptor protein signaling pathway; cell proliferation; vasoconstriction; positive regulation of microtubule depolymerization; behavioral fear response; serotonin receptor, adenylate cyclase inhibiting pathway; regulation of serotonin secretion; regulation of dopamine metabolic process; regulation of hormone secretion; serotonin receptor signaling pathway; serotonin metabolic process; regulation of behavior
Research Articles on Htr1a
1. Brain 5-HT1A receptors suppress defensive aggression in rats.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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