Product Name
(Rhesus macaque) Interleukin-6 (IL6), Recombinant Protein
Popular Item
Full Product Name
Recombinant Macaca mulatta (Rhesus macaque) Interleukin-6 (IL6)
Product Synonym Names
Recombinant (Rhesus macaque) Interleukin-6 (IL6); Interleukin-6; IL-6
Product Gene Name
IL6 recombinant protein
[Similar Products]
Product Synonym Gene Name
IL6[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
28-212
Sequence
APVLPGEDSK NVAAPHSQPL TSSERIDKHI RYILDGISAL RKETCNRSNM CESSKEALAE NNLNLPKMAE KDGCFQSGFN EDTCLVKIIT GLLEFEVYLE YLQNRFESSE EQARAVQMST KVLIQFLQKK AKNLDAITTP EPTTNASLLT KLQAQNQWLQ DMTTHLILRS FKEFLQSNLR ALRQM
Chromosome Location
Chromosome: 3; NC_007860.1 (103512775..103517082, complement). Location: chromosome: 3
3D Structure
ModBase 3D Structure for P51494
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>=90% (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Macaca mulatta (Rhesus macaque)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of IL6 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for IL6. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001036198.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001042733.1
[Other Products]
UniProt Primary Accession #
P51494
[Other Products]
UniProt Related Accession #
P51494[Other Products]
Molecular Weight
23,728 Da[Similar Products]
NCBI Official Full Name
interleukin-6
NCBI Official Symbol
IL6??[Similar Products]
NCBI Protein Information
interleukin-6; IL-6
UniProt Protein Name
Interleukin-6
Protein Family
Interleukin
UniProt Gene Name
IL6??[Similar Products]
UniProt Synonym Gene Names
IL-6??[Similar Products]
UniProt Entry Name
IL6_MACMU
UniProt Comments for IL6
Function: Cytokine with a wide variety of
biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance
By similarity.
Subcellular location: Secreted.
Sequence similarities: Belongs to the IL-6 superfamily.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.