Product Name
spastic paraplegia 11 (autosomal recessive) (SPG11), ELISA Kit
Full Product Name
Mouse Spatacsin, SPG11 ELISA Kit
Product Synonym Names
Mouse Spatacsin (SPG11) ELISA kit; FLJ21439; KIAA1840; ; spastic paraplegia 11 (autosomal recessive)
Product Gene Name
SPG11 elisa kit
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
Request Current Manual
3D Structure
ModBase 3D Structure for Q3UHA3
Preparation and Storage
Store all reagents at 2-8 degree C
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of SPG11 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for SPG11 purchase
MBS9338999 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the spastic paraplegia 11 (autosomal recessive) (SPG11) ELISA Kit target analytes in
biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing SPG11. The ELISA analytical biochemical technique of the MBS9338999 kit is based on SPG11 antibody-SPG11 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect SPG11 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, SPG11. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
NCBI/Uniprot data below describe general gene information for SPG11. It may not necessarily be applicable to this product.
NCBI Accession #
NP_663506.2
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NCBI GenBank Nucleotide #
NM_145531.2
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UniProt Primary Accession #
Q3UHA3
[Other Products]
UniProt Secondary Accession #
Q6ZPH3; Q8BHQ1; Q8C7R3; Q8C7U2; Q8CA88; Q8VEA5; A2ARM0[Other Products]
UniProt Related Accession #
Q3UHA3[Other Products]
Molecular Weight
273,934 Da
NCBI Official Full Name
spatacsin
NCBI Official Synonym Full Names
spastic paraplegia 11
NCBI Official Symbol
Spg11??[Similar Products]
NCBI Official Synonym Symbols
A330015I11; 6030465E24Rik; C530005A01Rik
??[Similar Products]
NCBI Protein Information
spatacsin; spastic paraplegia 11 protein homolog
UniProt Protein Name
Spatacsin
UniProt Synonym Protein Names
Spastic paraplegia 11 protein homolog
UniProt Gene Name
Spg11??[Similar Products]
UniProt Synonym Gene Names
Kiaa1840??[Similar Products]
UniProt Entry Name
SPTCS_MOUSE
UniProt Comments for SPG11
SPG11: Defects in SPG11 are the cause of spastic paraplegia autosomal recessive type 11 (SPG11). Spastic paraplegia is a neurodegenerative disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs. Rate of progression and the severity of symptoms are quite variable. Initial symptoms may include difficulty with balance, weakness and stiffness in the legs, muscle spasms, and dragging the toes when walking. In some forms of the disorder, bladder symptoms (such as incontinence) may appear, or the weakness and stiffness may spread to other parts of the body. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, multi-pass; Membrane protein, integral
Cellular Component: membrane; lysosomal membrane; cytoplasm; integral to membrane; plasma membrane; nucleolus; cytoplasmic vesicle; nucleus
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.