Product Name
N-acetyltransferase ESCO2 (ESCO2), Recombinant Protein
Full Product Name
Recombinant Human N-acetyltransferase ESCO2 (ESCO2)
Product Gene Name
ESCO2 recombinant protein
[Similar Products]
Product Synonym Gene Name
ESCO2[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
1-601aa, full length protein
Sequence
MAALTPRKRK QDSLKCDSLL HFTENLFPSP NKKHCFYQNS DKNEENLHCS QQEHFVLSAL KTTEINRLPS ANQGSPFKSA LSTVSFYNQN KWYLNPLERK LIKESRSTCL KTNDEDKSFP IVTEKMQGKP VCSKKNNKKP QKSLTAKYQP KYRHIKPVSR NSRNSKQNRV IYKPIVEKEN NCHSAENNSN APRVLSQKIK PQVTLQGGAA FFVRKKSSLR KSSLENEPSL GRTQKSKSEV IEDSDVETVS EKKTFATRQV PKCLVLEEKL KIGLLSASSK NKEKLIKDSS DDRVSSKEHK VDKNEAFSSE DSLGENKTIS PKSTVYPIFS ASSVNSKRSL GEEQFSVGSV NFMKQTNIQK NTNTRDTSKK TKDQLIIDAG QKHFGATVCK SCGMIYTASN PEDEMQHVQH HHRFLEGIKY VGWKKERVVA EFWDGKIVLV LPHDPSFAIK KVEDVQELVD NELGFQQVVP KCPNKIKTFL FISDEKRVVG CLIAEPIKQA FRVLSEPIGP ESPSSTECPR AWQCSDVPEP AVCGISRIWV FRLKRRKRIA RRLVDTLRNC FMFGCFLSTD EIAFSDPTPD GKLFATKYCN TPNFLVYNFN S
3D Structure
ModBase 3D Structure for Q56NI9
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of ESCO2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
ESCO2 recombinant protein
This gene encodes a protein that may have acetyltransferase activity and may be required for the establishment of sister chromatid cohesion during the S phase of mitosis. Mutations in this gene have been associated with Roberts syndrome.
NCBI/Uniprot data below describe general gene information for ESCO2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001017420.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001017420.2
[Other Products]
UniProt Primary Accession #
Q56NI9
[Other Products]
UniProt Secondary Accession #
Q49AP4; B3KW59[Other Products]
UniProt Related Accession #
Q56NI9[Other Products]
Molecular Weight
27,500 Da
NCBI Official Full Name
N-acetyltransferase ESCO2
NCBI Official Synonym Full Names
establishment of sister chromatid cohesion N-acetyltransferase 2
NCBI Official Symbol
ESCO2??[Similar Products]
NCBI Official Synonym Symbols
RBS; EFO2; 2410004I17Rik
??[Similar Products]
NCBI Protein Information
N-acetyltransferase ESCO2
UniProt Protein Name
N-acetyltransferase ESCO2
UniProt Synonym Protein Names
Establishment of cohesion 1 homolog 2; ECO1 homolog 2
Protein Family
N-acetyltransferase
UniProt Gene Name
ESCO2??[Similar Products]
UniProt Synonym Gene Names
ECO1 homolog 2??[Similar Products]
NCBI Summary for ESCO2
This gene encodes a protein that may have acetyltransferase activity and may be required for the establishment of sister chromatid cohesion during the S phase of mitosis. Mutations in this gene have been associated with Roberts syndrome. [provided by RefSeq, Jul 2008]
UniProt Comments for ESCO2
Acetyltransferase required for the establishment of sister chromatid cohesion. Couples the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together. In contrast to the structural cohesins, the deposition and establishment factors are required only during the S phase. Acetylates the cohesin component SMC3.
Research Articles on ESCO2
1. ESCO2 knockdown inhibits cell proliferation and induces apoptosis in human gastric cancer cells.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
