Product Name
C5a anaphylatoxin chemotactic receptor (C5AR1), Recombinant Protein
Full Product Name
Recombinant Dog C5a anaphylatoxin chemotactic receptor (C5AR1)
Product Synonym Names
Recombinant C5a anaphylatoxin chemotactic receptor (C5AR1); C5a anaphylatoxin chemotactic receptor; C5a-R; C5aR; CD_antigen= CD88
Product Gene Name
C5AR1 recombinant protein
[Similar Products]
Product Synonym Gene Name
C5AR1; C5R1[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
MASMNFSPPE YPDYGTATLD PNIFVDESLN TPKLSVPDMI ALVIFVMVFL VGVPGNFLVV WVTGFEVRRT INAIWFLNLA VADLLSCLAL PILFSSIVQQ GYWPFGNAAC RILPSLILLN MYASILLLTT ISADRFVLVF NPIWCQNYRG PQLAWAACSV AWAVALLLTV PSFIFRGVHT EYFPFWMTCG VDYSGVGVLV ERGVAILRLL MGFLGPLVIL SICYTFLLIR TWSRKATRST KTLKVVVAVV VSFFVLWLPY QVTGMMMALF YKHSESFRRV SRLDSLCVAV AYINCCINPI IYVLAAQGFH SRFLKSLPAR LRQVLAEESV GRDSKSITLS TVDTPAQKSQ GV
Chromosome Location
Chromosome: 1; NC_006583.3 (108659637..108675401, complement). Location: chromosome: 1
3D Structure
ModBase 3D Structure for P30992
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>=90% (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Canis familiaris (Dog) (Canis lupus familiaris)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of C5AR1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for C5AR1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001003373.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001003373.1
[Other Products]
UniProt Primary Accession #
P30992
[Other Products]
UniProt Related Accession #
P30992[Other Products]
Molecular Weight
39,213 Da[Similar Products]
NCBI Official Full Name
C5a anaphylatoxin chemotactic receptor
NCBI Official Symbol
C5AR1??[Similar Products]
NCBI Official Synonym Symbols
C5R1
??[Similar Products]
NCBI Protein Information
C5a anaphylatoxin chemotactic receptor; C5aR; C5a-R; complement C5a receptor; complement component 5 receptor 1 (C5a ligand)
UniProt Protein Name
C5a anaphylatoxin chemotactic receptor
Protein Family
C5a anaphylatoxin chemotactic receptor
UniProt Gene Name
C5AR1??[Similar Products]
UniProt Synonym Gene Names
C5R1; C5a-R; C5aR??[Similar Products]
UniProt Entry Name
C5AR_CANFA
UniProt Comments for C5AR1
Function: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.
Subunit structure: Interacts with ARRB1 and ARRB2
By similarity.
Subcellular location: Cell membrane; Multi-pass membrane protein.
Post-translational modification: Sulfation plays a critical role in the association of C5aR with C5a, but no significant role in the ability of the receptor to transduce a signal and mobilize calcium in response to a small peptide agonist
By similarity.
Sequence similarities: Belongs to the G-protein coupled receptor 1 family.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
