Full Product Name
ACSF3 Antibody
Product Gene Name
anti-ACSF3 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q4G176
Form/Format
Purified by peptide affinity column containing 0.5% BSA and 0.02% NaN3
Preparation and Storage
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.
Other Notes
Small volumes of anti-ACSF3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ACSF3 antibody
Rabbit polyclonal ACSF3 (1) antibody was raised against a 16 amino acid peptide from intermediate residues of human ACSF3 protein.
Product Categories/Family for anti-ACSF3 antibody
Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
Applications Tested/Suitable for anti-ACSF3 antibody
Peptide ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-ACSF3 antibody
Peptide ELISA: 1:40,000-80,000
WB: 1:1,000-2,000
IHC: 1:100-500
Testing Data of anti-ACSF3 antibody
Testing Data of anti-ACSF3 antibody
NCBI/Uniprot data below describe general gene information for ACSF3. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001120686.1
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NCBI GenBank Nucleotide #
NM_001127214.3
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UniProt Primary Accession #
Q4G176
[Other Products]
UniProt Secondary Accession #
Q6INA0; Q8N2F7; A8K4J8; C9JQL6[Other Products]
UniProt Related Accession #
Q4G176[Other Products]
Molecular Weight
64,130 Da
NCBI Official Full Name
acyl-CoA synthetase family member 3, mitochondrial isoform 1
NCBI Official Synonym Full Names
acyl-CoA synthetase family member 3
NCBI Official Symbol
ACSF3??[Similar Products]
NCBI Protein Information
acyl-CoA synthetase family member 3, mitochondrial
UniProt Protein Name
Acyl-CoA synthetase family member 3, mitochondrial
Protein Family
Acyl-CoA synthetase family
UniProt Gene Name
ACSF3??[Similar Products]
NCBI Summary for ACSF3
This gene encodes a member of the acyl-CoA synthetase family of enzymes that activate fatty acids by catalyzing the formation of a thioester linkage between fatty acids and coenzyme A. The encoded protein is localized to mitochondria, has high specificity for malonate and methylmalonate and possesses malonyl-CoA synthetase activity. Mutations in this gene are a cause of combined malonic and methylmalonic aciduria. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Sep 2013]
UniProt Comments for ACSF3
Catalyzes the initial reaction in intramitochondrial fatty acid synthesis, by activating malonate and methylmalonate, but not acetate, into their respective CoA thioester. May have some preference toward very-long-chain substrates.
Product References and Citations for anti-ACSF3 antibody
(1) Watkins, P.A., Maiguel, D., Jia, Z. and Pevsner, J. Evidence for 26 distinct acyl-coenzyme A synthetase genes in the human genome. J. Lipid Res. 48 (12), 2736-2750 (2007).
Research Articles on ACSF3
1. an essential role for ACSF3 in dictating the metabolic fate of mitochondrial malonate and malonyl-CoA in mammalian metabolism
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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