Product Name
C5AR1, cDNA Clone
Popular Item
Full Product Name
C5AR1 cDNA Clone
Product Gene Name
C5AR1 cdna clone
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence
atgaactcct tcaattatac cacccctgat tatgggcact atgatgacaa ggataccctg gacctcaaca cccctgtgga taaaacttct aacacgctgc gtgttccaga catcctggcc ttggtcatct ttgcagtcgt cttcctggtg ggagtgctgg gcaatgccct ggtggtctgg gtgacggcat tcgaggccaa gcggaccatc aatgccatct ggttcctcaa cttggcggta gccgacttcc tctcctgcct ggcgctgccc atcttgttca cgtccattgt acagcatcac cactggccct ttggcggggc cgcctgcagc atcctgccct ccctcatcct gctcaacatg tacgccagca tcctgctcct ggccaccatc agcgccgacc gctttctgct ggtgtttaaa cccatctggt gccagaactt ccgaggggcc ggcttggcct ggatcgcctg tgccgtggct tggggtttag ccctgctgct gaccataccc tccttcctgt accgggtggt ccgggaggag tactttccac caaaggtgtt gtgtggcgtg gactacagcc acgacaaacg gcgggagcga gccgtggcca tcgtccggct ggtcctgggc ttcctgtggc ctctactcac gctcacgatt tgttacactt tcatcctgct ccggacgtgg agccgcaggg ccacgcggtc caccaagaca ctcaaggtgg tggtggcagt ggtggccagt ttctttatct tctggttgcc ctaccaggtg acggggataa tgatgtcctt cctggagcca tcgtcaccca ccttcctgct gctgaataag ctggactccc tgtgtgtctc ctttgcctac atcaactgct gcatcaaccc catcatctac gtggtggccg gccagggctt ccagggccga ctgcggaaat ccctccccag cctcctccgg aacgtgttga ctgaagagtc cgtggttagg gagagcaagt cattcacgcg ctccacagtg gacactatgg cccagaagac ccaggcagtg tag
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of C5AR1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for C5AR1. It may not necessarily be applicable to this product.
NCBI Accession #
BC008982
[Other Products]
UniProt Related Accession #
P21730[Other Products]
Molecular Weight
39,336 Da
NCBI Official Full Name
Homo sapiens complement component 5a receptor 1, mRNA
NCBI Official Synonym Full Names
complement C5a receptor 1
NCBI Official Symbol
C5AR1??[Similar Products]
NCBI Official Synonym Symbols
C5A; C5AR; C5R1; CD88
??[Similar Products]
NCBI Protein Information
C5a anaphylatoxin chemotactic receptor 1
UniProt Protein Name
C5a anaphylatoxin chemotactic receptor 1
UniProt Synonym Protein Names
C5a anaphylatoxin chemotactic receptor; C5a-R; C5aR; CD_antigen: CD88
Protein Family
C5a anaphylatoxin chemotactic receptor
UniProt Gene Name
C5AR1??[Similar Products]
UniProt Synonym Gene Names
C5AR; C5R1; C5a-R; C5aR??[Similar Products]
UniProt Entry Name
C5AR1_HUMAN
UniProt Comments for C5AR1
C5aR: a family 1 G-protein coupled receptor that stimulates the GTPase activity of Gi2. Receptor for the chemotactic and inflammatory complement factor C5a. Stimulates chemotaxis, granule enzyme release and superoxide anion production. Phosphorylated in response to C5a or after stimulation of cells with phorbol esters. Expressed on monocytes, granulocytes, dendritic cells, astrocytes and microglia.
Protein type: Membrane protein, multi-pass; Membrane protein, integral; Receptor, GPCR; GPCR, family 1
Chromosomal Location of Human Ortholog: 19q13.3-q13.4
Cellular Component: apical part of cell; basolateral plasma membrane; integral to plasma membrane; plasma membrane
Molecular Function: complement component C5a receptor activity
Biological Process: activation of MAPK activity; cellular defense response; chemotaxis; immune response; mRNA transcription from RNA polymerase II promoter; phospholipase C activation; positive regulation of epithelial cell proliferation; regulation of complement activation; sensory perception of chemical stimulus; signal transduction
Research Articles on C5AR1
1. that C5aR stimulates cell invasion and migration via ERK1/2-mediated epithelial-mesenchymal transition in hepatocellular carcinoma cells
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
