Anti -C5AR1, ID (C5AR1, C5AR, C5R1, C5a anaphylatoxin chemotactic receptor, CD88)

For Research Use Only. Not for use in diagnostic procedures.

Chromosome: 19; NC_000019.9 (47813104..47825327). Location: 19q13.3-q13.4

Polyclonal

IgG

Rabbit

Human

Affinity Purified
Purified by Protein A affinity chromatography.

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Small volumes of anti-C5AR1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.

Antibodies; Abs to CD Markers

ELISA (EL/EIA), Western Blot (WB), Flow Cytometry (FC/FACS)

Suitable for use in Western Blot, Flow Cytometry, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500
Flow Cytometry: 1:10-50

39,336 Da[Similar Products]

complement component 5a receptor 1

C5a anaphylatoxin chemotactic receptor 1; C5a-R; C5a ligand; C5a anaphylatoxin receptor; complement component 5 receptor 1

C5a anaphylatoxin chemotactic receptor 1

C5AR; C5R1; C5a-R; C5aR??[Similar Products]

C5AR1_HUMAN

Function: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.

Subunit structure: Interacts with ARRB1 and ARRB2

By similarity.

Subcellular location: Cell membrane; Multi-pass membrane protein.

Post-translational modification: Sulfation plays a critical role in the association of the receptor with C5a, but no significant role in the ability of the receptor to transduce a signal and mobilize calcium in response to a small peptide agonist.

Sequence similarities: Belongs to the G-protein coupled receptor 1 family.

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