Full Product Name
CD88 (Phospho-Ser327) Antibody
Product Gene Name
anti-CD88 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P21730
Concentration
1.0mg/ml (lot specific)
Other Notes
Small volumes of anti-CD88 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-CD88 antibody
Western Blot (WB)
NCBI/Uniprot data below describe general gene information for CD88. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001727.1
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NCBI GenBank Nucleotide #
NM_001736.3
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UniProt Primary Accession #
P21730
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UniProt Related Accession #
P21730[Other Products]
Molecular Weight
39,336 Da
NCBI Official Full Name
C5a anaphylatoxin chemotactic receptor 1
NCBI Official Synonym Full Names
complement C5a receptor 1
NCBI Official Symbol
C5AR1??[Similar Products]
NCBI Official Synonym Symbols
C5A; C5AR; C5R1; CD88
??[Similar Products]
NCBI Protein Information
C5a anaphylatoxin chemotactic receptor 1
UniProt Protein Name
C5a anaphylatoxin chemotactic receptor 1
UniProt Synonym Protein Names
C5a anaphylatoxin chemotactic receptor; C5a-R; C5aR; CD_antigen: CD88
UniProt Gene Name
C5AR1??[Similar Products]
UniProt Synonym Gene Names
C5AR; C5R1; C5a-R; C5aR??[Similar Products]
UniProt Comments for CD88
C5aR: a family 1 G-protein coupled receptor that stimulates the GTPase activity of Gi2. Receptor for the chemotactic and inflammatory complement factor C5a. Stimulates chemotaxis, granule enzyme release and superoxide anion production. Phosphorylated in response to C5a or after stimulation of cells with phorbol esters. Expressed on monocytes, granulocytes, dendritic cells, astrocytes and microglia.
Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR
Chromosomal Location of Human Ortholog: 19q13.32
Cellular Component: apical part of cell; basolateral plasma membrane; integral to plasma membrane; plasma membrane
Molecular Function: complement component C5a receptor activity; G-protein coupled receptor activity
Biological Process: activation of MAPK activity; cellular defense response; chemotaxis; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); immune response; inflammatory response; leukocyte migration; mRNA transcription from RNA polymerase II promoter; phospholipase C activation; positive regulation of epithelial cell proliferation; regulation of complement activation; sensory perception of chemical stimulus; signal transduction
Research Articles on CD88
1. Relation of C5aR expression to tumor development and poor prognosis of the breast cancer patients
Precautions
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Disclaimer
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