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Chorionic somatomammotropin hormone, Polyclonal Antibody

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產(chǎn)品名稱: Chorionic somatomammotropin hormone, Polyclonal Antibody
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Chorionic somatomammotropin hormone, Polyclonal Antibody


Chorionic somatomammotropin hormone, Polyclonal Antibody  的詳細(xì)介紹
Product Name

Chorionic somatomammotropin hormone (CSH1), Polyclonal Antibody

Popular Item
Full Product Name

Rabbit anti-human Chorionic somatomammotropin hormone polyclonal Antibody

Product Synonym Names
Lactogen; Placental lactogen; CSH1; CSH2
Product Gene Name

anti-CSH1 antibody

[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
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OMIM
150200
3D Structure
ModBase 3D Structure for P0DML2
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Purity/Purification
Caprylic Acid Ammonium Sulfate Precipitation Purified
Storage Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Conjugate
Non-conjugated
Immunogen
Recombinant human Chorionic somatomammotropin hormone protein
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of anti-CSH1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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Related Product Information for
anti-CSH1 antibody
Produced only during pregnancy and is involved in stimulating lactation, fetal growth and metabolism. Does not interact with GHR but only activates PRLR through zinc-induced dimerization.
Applications Tested/Suitable for anti-CSH1 antibody
ELISA (EIA), Western Blot (WB)

Western Blot (WB) of anti-CSH1 antibody
Western blot
All lanes: Chorionic somatomammotropin hormone antibody at 2ug/ml
Lane 1: A549 whole cell lysate
Lane 2: u251 whole cell lysate
Secondary
Goat polyclonal to Rabbit IgG at 1/15000 dilution
Predicted band size: 25 kDa
Observed band size: 25kDa

anti-CSH1 antibody Western Blot (WB) (WB) image
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NCBI/Uniprot data below describe general gene information for CSH1. It may not necessarily be applicable to this product.
NCBI GI #
4503083
NCBI GeneID
1442
NCBI Accession #
NP_001308.1 [Other Products]
NCBI GenBank Nucleotide #
NM_001317.5 [Other Products]
UniProt Primary Accession #
P0DML2 [Other Products]
UniProt Secondary Accession #
P01243; Q0VDB1; Q14407[Other Products]
UniProt Related Accession #
P0DML2[Other Products]
Molecular Weight
25,020 Da[Similar Products]
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NCBI Official Full Name
chorionic somatomammotropin hormone 1
NCBI Official Synonym Full Names
chorionic somatomammotropin hormone 1
NCBI Official Symbol
CSH1??[Similar Products]
NCBI Official Synonym Symbols
PL; CSA; CS-1; CSMT; GHB3; hCS-1; hCS-A
??[Similar Products]
NCBI Protein Information
chorionic somatomammotropin hormone 1
UniProt Protein Name
Chorionic somatomammotropin hormone 1
UniProt Synonym Protein Names
Lactogen; Placental lactogen; PL
Protein Family
Chorionic somatomammotropin hormone
UniProt Gene Name
CSH1??[Similar Products]
UniProt Synonym Gene Names
Choriomammotropin; PL??[Similar Products]
UniProt Entry Name
CSH1_HUMAN
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NCBI Summary for CSH1
The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, although the ratio of 1 to 2 increases by term. Mutations in this gene result in placental lactogen deficiency and Silver-Russell syndrome. [provided by RefSeq, Jul 2008]
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UniProt Comments for CSH1
CSH1: Produced only during pregnancy and is involved in stimulating lactation, fetal growth and metabolism. Does not interact with GHR but only activates PRLR through zinc-induced dimerization. Belongs to the somatotropin/prolactin family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 17q24.2

Cellular Component: endoplasmic reticulum; extracellular region

Molecular Function: hormone activity; metal ion binding
Research Articles on CSH1
1. Placental lactogen is expressed but is not translated into protein in breast cancer.
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Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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