Full Product Name
ABCB5 Antibody
Product Gene Name
anti-ABCB5 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q2M3G0
Species Reactivity
Human
Predicted: Mouse, Rat
Form/Format
Purified by protein affinity column containing 0.02% NaN3
Preparation and Storage
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C after reconstitution. Avoid repeated freeze/defrost cycles.
Other Notes
Small volumes of anti-ABCB5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-ABCB5 antibody
Rabbit polyclonal ABCB5 (1) antibody was raised against a recombinate human ABCB5 protein 587-790aa (BC104894).
Product Categories/Family for anti-ABCB5 antibody
Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
Applications Tested/Suitable for anti-ABCB5 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-ABCB5 antibody
ELISA: 1:20,000-1:80,000
WB: 1:500-1:1,000
IHC: 1:100-1:500
Testing Data of anti-ABCB5 antibody
Testing Data of anti-ABCB5 antibody
NCBI/Uniprot data below describe general gene information for ABCB5. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001157465.1
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NCBI GenBank Nucleotide #
NM_001163993.2
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UniProt Primary Accession #
Q2M3G0
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UniProt Secondary Accession #
Q2M3I5; Q5I5Q7; Q5I5Q8; Q6KG50; A4D131; A7BKA4; B5MD19; B7WPL1; F8QQP8; F8QQP9; J3KQ04[Other Products]
UniProt Related Accession #
Q2M3G0[Other Products]
Molecular Weight
89,832 Da
NCBI Official Full Name
ATP-binding cassette sub-family B member 5 isoform 4
NCBI Official Synonym Full Names
ATP binding cassette subfamily B member 5
NCBI Official Symbol
ABCB5??[Similar Products]
NCBI Official Synonym Symbols
ABCB5beta; EST422562; ABCB5alpha
??[Similar Products]
NCBI Protein Information
ATP-binding cassette sub-family B member 5
UniProt Protein Name
ATP-binding cassette sub-family B member 5
UniProt Synonym Protein Names
ABCB5 P-gp; P-glycoprotein ABCB5
Protein Family
ABC transporter B family
UniProt Gene Name
ABCB5??[Similar Products]
NCBI Summary for ABCB5
ABCB5 belongs to the ATP-binding cassette (ABC) transporter superfamily of integral membrane proteins. These proteins participate in ATP-dependent transmembrane transport of structurally diverse molecules ranging from small ions, sugars, and peptides to more complex organic molecules (Chen et al., 2005 [PubMed 15760339]).[supplied by OMIM, Mar 2008]
UniProt Comments for ABCB5
Drug efflux transporter present in a number of stem cells that acts as a regulator of cellular differentiation. Able to mediate efflux from cells of the rhodamine dye and of the therapeutic drug doxorubicin. Specifically present in limbal stem cells, where it plays a key role in corneal development and repair.
Product References and Citations for anti-ABCB5 antibody
(1) Frank, N.Y. and Frank, M.H. ABCB5 gene amplification in human leukemia cells. Leuk. Res. 33 (10), 1303-1305 (2009).
Research Articles on ABCB5
1. No significant influence of the three newly identified ABCB5 polymorphisms.
Precautions
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Disclaimer
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