Full Product Name
CSH1 Antibody
Product Synonym Names
CSA; CSMT; FLJ75407; PL
Product Gene Name
anti-CSH1 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Purity/Purification
Antigen affinity purification
Immunogen
Peptide of CSH1
Calculated Molecular Weight: 25kd
Observed Molecular Weight: 23-25kd
Buffer
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-CSH1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-CSH1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-CSH1 antibody
WB: 1:200-1:2000
IHC: 1:20-1:200
Testing Data of anti-CSH1 antibody
NCBI/Uniprot data below describe general gene information for CSH1. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001308.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001317.5
[Other Products]
UniProt Secondary Accession #
P01243; Q0VDB1; Q14407[Other Products]
UniProt Related Accession #
P0DML2[Other Products]
Molecular Weight
25,020 Da
NCBI Official Full Name
chorionic somatomammotropin hormone 1
NCBI Official Synonym Full Names
chorionic somatomammotropin hormone 1 (placental lactogen)
NCBI Official Symbol
CSH1??[Similar Products]
NCBI Official Synonym Symbols
PL; CSA; CS-1; CSMT; hCS-1; hCS-A
??[Similar Products]
NCBI Protein Information
chorionic somatomammotropin hormone 1; choriomammotropin; chorionic somatomammotropin A; chorionic somatomammotropin-1; placental lactogen
UniProt Protein Name
Chorionic somatomammotropin hormone 1
UniProt Synonym Protein Names
Lactogen; Placental lactogen; PL
Protein Family
Chorionic somatomammotropin hormone
UniProt Gene Name
CSH1??[Similar Products]
UniProt Synonym Gene Names
Choriomammotropin; PL??[Similar Products]
UniProt Entry Name
CSH1_HUMAN
NCBI Summary for CSH1
The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, although the ratio of 1 to 2 increases by term. Mutations in this gene result in placental lactogen deficiency and Silver-Russell syndrome. [provided by RefSeq, Jul 2008]
UniProt Comments for CSH1
CSH1: Produced only during pregnancy and is involved in stimulating lactation, fetal growth and metabolism. Does not interact with GHR but only activates PRLR through zinc-induced dimerization. Belongs to the somatotropin/prolactin family.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 17q24.2
Cellular Component: extracellular region
Molecular Function: metal ion binding; hormone activity
Research Articles on CSH1
1. These results indicate that placental lactogen induces CYP2E1 expression via PI3-kinase pathway in human hepatocytes.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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