Full Product Name
Human CSH1 Polyclonal Antibody
Product Synonym Names
Lactogen; Placental lactogen; PL
Product Gene Name
anti-CSH1 antibody
[Similar Products]
Matching Pairs
Antibody: CSH1 (MBS2895316)
Antigen: Chorionic somatomammotropin hormone (MBS2889016)
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P01243
Purity/Purification
Immunogen Affinity Purified
Form/Format
Liquid; 0.1MxPBS, 50% Glycerol, pH7.5
Concentration
200 ug/ml (lot specific)
Immunogen
Recombinant Human CSH1 Protein
Preparation and Storage
Store at 4 degree C for frequent use. Store at -20 degree C to -70 degree C for 6 months.
Other Notes
Small volumes of anti-CSH1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-CSH1 antibody
Western Blot (WB), Immunohistochemistry (IHC)
NCBI/Uniprot data below describe general gene information for CSH1. It may not necessarily be applicable to this product.
NCBI Accession #
AAA98621.1
[Other Products]
UniProt Primary Accession #
P01243
[Other Products]
UniProt Related Accession #
P0DML2[Other Products]
NCBI Official Full Name
placental lactogen
NCBI Official Synonym Full Names
chorionic somatomammotropin hormone 1
NCBI Official Symbol
CSH1??[Similar Products]
NCBI Official Synonym Symbols
PL; CSA; CS-1; CSMT; GHB3; hCS-1; hCS-A
??[Similar Products]
NCBI Protein Information
chorionic somatomammotropin hormone 1
UniProt Protein Name
Chorionic somatomammotropin hormone
UniProt Synonym Protein Names
Lactogen; Placental lactogen
Protein Family
Chorionic somatomammotropin hormone
UniProt Gene Name
CSH1??[Similar Products]
UniProt Synonym Gene Names
Choriomammotropin; PL??[Similar Products]
UniProt Entry Name
CSH_HUMAN
NCBI Summary for CSH1
The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, although the ratio of 1 to 2 increases by term. Mutations in this gene result in placental lactogen deficiency and Silver-Russell syndrome. [provided by RefSeq, Jul 2008]
UniProt Comments for CSH1
CSH1: Produced only during pregnancy and is involved in stimulating lactation, fetal growth and metabolism. Does not interact with GHR but only activates PRLR through zinc-induced dimerization. Belongs to the somatotropin/prolactin family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 17q24.2
Cellular Component: extracellular region
Molecular Function: hormone activity; metal ion binding
Research Articles on CSH1
1. FGF-2b and hPL-A are promising candidates for regenerative therapy in Diabetes Mellitus by inducing de-differentiation of stem cells modulating pivotal endocrine genes.
Precautions
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Disclaimer
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