Full Product Name
CYBA Polyclonal Antibody
Product Synonym Names
p22-PHOX
Product Gene Name
anti-CYBA antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Immunogen Sequence
VRGEQWTPIE PKPRERPQIG GTIKQPPSNP PPRPPAEARK KPSEEEAAVA AGGPPGGPQV NPIPVTDEVV
3D Structure
ModBase 3D Structure for P13498
Purity/Purification
Affinity Purification
Immunogen
Recombinant protein of human CYBA
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Cellular Location
Cell membrane
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.
Other Notes
Small volumes of anti-CYBA antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-CYBA antibody
Cytochrome b is comprised of a light chain (alpha) and a heavy chain (beta). This gene encodes the light, alpha subunit which has been proposed as a primary component of the microbicidal oxidase system of phagocytes. Mutations in this gene are associated with autosomal recessive chronic granulomatous disease (CGD), that is characterized by the failure of activated phagocytes to generate superoxide, which is important for the microbicidal activity of these cells.
Product Categories/Family for anti-CYBA antibody
Polyclonal Antibodies
Applications Tested/Suitable for anti-CYBA antibody
Immunofluorescence (IF)
Application Notes for anti-CYBA antibody
IF: 1:50 - 1:100
NCBI/Uniprot data below describe general gene information for CYBA. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000092.2
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NCBI GenBank Nucleotide #
NM_000101.3
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UniProt Primary Accession #
P13498
[Other Products]
UniProt Secondary Accession #
Q14090; Q9BR72[Other Products]
UniProt Related Accession #
P13498[Other Products]
NCBI Official Full Name
cytochrome b-245 light chain
NCBI Official Synonym Full Names
cytochrome b-245 alpha chain
NCBI Official Symbol
CYBA??[Similar Products]
NCBI Official Synonym Symbols
p22-PHOX
??[Similar Products]
NCBI Protein Information
cytochrome b-245 light chain
UniProt Protein Name
Cytochrome b-245 light chain
UniProt Synonym Protein Names
Cytochrome b(558) alpha chain; Cytochrome b558 subunit alpha; Neutrophil cytochrome b 22 kDa polypeptide; Superoxide-generating NADPH oxidase light chain subunit; p22 phagocyte B-cytochrome; p22-phox; p22phox
Protein Family
Cytochrome
UniProt Gene Name
CYBA??[Similar Products]
UniProt Synonym Gene Names
p22phox??[Similar Products]
NCBI Summary for CYBA
Cytochrome b is comprised of a light chain (alpha) and a heavy chain (beta). This gene encodes the light, alpha subunit which has been proposed as a primary component of the microbicidal oxidase system of phagocytes. Mutations in this gene are associated with autosomal recessive chronic granulomatous disease (CGD), that is characterized by the failure of activated phagocytes to generate superoxide, which is important for the microbicidal activity of these cells. [provided by RefSeq, Jul 2008]
UniProt Comments for CYBA
Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.
Research Articles on CYBA
1. Suggest that the C242T gene polymorphism is associated with arterial stiffness. Additionally, this relationship could be modified by smoking dose.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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