Product Name
A1AT, Monoclonal Antibody
Popular Item
Full Product Name
A1AT Antibody
Product Gene Name
anti-A1AT antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P01009
Specificity
Anti-A1AT recognizes recombinant protein A1AT.
Form/Format
Each vial contains 100 ug IgG in 100 ul of citrate-tris-HCl buffer pH7.0 with 0.02% Proclin 300.
Immunogen
Recombinant protein corresponding to fragment (aa/25-418) A1AT.
Preparation and Storage
The antibody may be stored at-20 degree C for one year in its original formulation. Additionally, antibody may be stored at 2 degree C to 8 degree C for up to 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles of the diluted antibody.
Other Notes
Small volumes of anti-A1AT antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-A1AT antibody
Purified mouse monoclonal antibody generated using E Coli expressed recombinant protein A1AT as immunogen.
Product Categories/Family for anti-A1AT antibody
Plant antibody
NCBI/Uniprot data below describe general gene information for A1AT. It may not necessarily be applicable to this product.
NCBI Accession #
NP_000286.3
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NCBI GenBank Nucleotide #
NM_000295.4
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UniProt Primary Accession #
P01009
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UniProt Secondary Accession #
Q0PVP5; Q13672; Q53XB8; Q5U0M1; Q7M4R2; Q86U18; Q86U19; Q96BF9; Q96ES1; A6PX14; B2RDQ8[Other Products]
UniProt Related Accession #
P01009[Other Products]
Molecular Weight
34,755 Da
NCBI Official Full Name
alpha-1-antitrypsin
NCBI Official Synonym Full Names
serpin family A member 1
NCBI Official Symbol
SERPINA1??[Similar Products]
NCBI Official Synonym Symbols
PI; A1A; AAT; PI1; A1AT; nNIF; PRO2275; alpha1AT
??[Similar Products]
NCBI Protein Information
alpha-1-antitrypsin
UniProt Protein Name
Alpha-1-antitrypsin
UniProt Synonym Protein Names
Alpha-1 protease inhibitor; Alpha-1-antiproteinase; Serpin A1
UniProt Gene Name
SERPINA1??[Similar Products]
UniProt Synonym Gene Names
AAT; PI; SPAAT??[Similar Products]
NCBI Summary for A1AT
The protein encoded by this gene is secreted and is a serine protease inhibitor whose targets include elastase, plasmin, thrombin, trypsin, chymotrypsin, and plasminogen activator. Defects in this gene can cause emphysema or liver disease. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
UniProt Comments for A1AT
Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin.
Research Articles on A1AT
1. A1AT polymorphisms may be associated with human retrovirus infections in an ethnically mixed population from the Amazon region of Brazil.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
