Full Product Name
Anti-DYM Antibody
Product Gene Name
anti-DYM antibody
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Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Purity/Purification
Affinity Purification
Concentration
1mg/ml (lot specific)
Immunogen
Recombinant protein of human DYM
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.
Other Notes
Small volumes of anti-DYM antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
anti-DYM antibody
This gene encodes a protein which is necessary for normal skeletal development and brain function.
Applications Tested/Suitable for anti-DYM antibody
Western Blot (WB)
Application Notes for anti-DYM antibody
WB: 1:500-1:2000
NCBI/Uniprot data below describe general gene information for DYM. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001340140.1
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NCBI GenBank Nucleotide #
NM_001353211.1
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UniProt Secondary Accession #
Q3ZTS8; Q6P2P5; Q8N2M0; Q9BVE9; Q9NPU7; A8K5I8; B2RCF9; B4DKI7[Other Products]
UniProt Related Accession #
Q7RTS9[Other Products]
Molecular Weight
54,425 Da
NCBI Official Full Name
dymeclin isoform 3
NCBI Official Synonym Full Names
dymeclin
NCBI Official Symbol
DYM??[Similar Products]
NCBI Official Synonym Symbols
DMC; SMC
??[Similar Products]
NCBI Protein Information
dymeclin
UniProt Protein Name
Dymeclin
UniProt Synonym Protein Names
Dyggve-Melchior-Clausen syndrome protein
UniProt Gene Name
DYM??[Similar Products]
NCBI Summary for DYM
This gene encodes a protein which regulates Golgi-associated secretory pathways that are essential to endochondral bone formation during early development. This gene is also believed to play a role in early brain development. This gene is widely expressed in embryos and is particularly abundant in chodrocytes and brain tissues. It encodes a peripheral membrane protein which shuttles between the cytosol and Golgi complex. Mutations in this gene are associated with two types of recessive osteochondrodysplasia: Dyggve-Melchior-Clausen (DMC) dysplasia and Smith-McCort (SMC) dysplasia. [provided by RefSeq, Jun 2017]
UniProt Comments for DYM
Necessary for correct organization of Golgi apparatus. Involved in bone development.
Research Articles on DYM
1. Dymeclin is crucial for proper myelination and anterograde neuronal trafficking, two processes that are highly active during postnatal brain maturation.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
