Full Product Name
GPD1L Antibody
Product Gene Name
anti-GPD1L antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Other Notes
Small volumes of anti-GPD1L antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Testing Data of anti-GPD1L antibody
NCBI/Uniprot data below describe general gene information for GPD1L. It may not necessarily be applicable to this product.
NCBI Accession #
BC028726
[Other Products]
UniProt Secondary Accession #
Q14702; Q9BRM5; A8K9U3[Other Products]
UniProt Related Accession #
Q8N335[Other Products]
Molecular Weight
38,419 Da
NCBI Official Full Name
Homo sapiens glycerol-3-phosphate dehydrogenase 1-like, mRNA
NCBI Official Synonym Full Names
glycerol-3-phosphate dehydrogenase 1 like
NCBI Official Symbol
GPD1L??[Similar Products]
NCBI Official Synonym Symbols
GPD1-L
??[Similar Products]
NCBI Protein Information
glycerol-3-phosphate dehydrogenase 1-like protein
UniProt Protein Name
Glycerol-3-phosphate dehydrogenase 1-like protein
Protein Family
Glycerol-3-phosphate dehydrogenase 1-like protein
UniProt Gene Name
GPD1L??[Similar Products]
UniProt Synonym Gene Names
KIAA0089; GPD1-L??[Similar Products]
NCBI Summary for GPD1L
The protein encoded by this gene catalyzes the conversion of sn-glycerol 3-phosphate to glycerone phosphate. The encoded protein is found in the cytoplasm, associated with the plasma membrane, where it binds the sodium channel, voltage-gated, type V, alpha subunit (SCN5A). Defects in this gene are a cause of Brugada syndrome type 2 (BRS2) as well as sudden infant death syndrome (SIDS). [provided by RefSeq, Jul 2010]
UniProt Comments for GPD1L
Plays a role in regulating cardiac sodium current; decreased enzymatic activity with resulting increased levels of glycerol 3-phosphate activating the DPD1L-dependent SCN5A phosphorylation pathway, may ultimately lead to decreased sodium current; cardiac sodium current may also be reduced due to alterations of NAD(H) balance induced by DPD1L.
Research Articles on GPD1L
1. Then bioinformatic analysis identified potential target sites of the miR-181a located in the 3' untranslated region of GPD1L. Increased GPD1L and decreased miRNA-181a were observed in tissues from osteoarthritis patients. Our results demonstrated that miR-181a may play an important role in the pathogenesis of Osteoarthritis through targeting GPD1L and regulating chondrocyte apoptosis.
Precautions
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Disclaimer
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