Anti -ABCB10 (ABCB10 ATP Binding Cassette, Sub-family B (MDR/TAP) Member 10, ATP-binding Cassette Sub-family B Member 10 Mitochondrial, ABCB 10, ATP-binding Cassette Transporter 10, ABC Transporter 10 Protein, EST20237, Mitochondrial ATP Binding Cassette 2, M A

For Research Use Only. Not for use in diagnostic procedures.

Chromosome: 1; NC_000001.10 (229652329..229694442, complement). Location: 1q42.13

Polyclonal

Goat

Recognizes human ABCB10. Species Crossreactivity: Mouse and rat.

Affinity Purified
Purified by immunoaffinity chromatography.

Supplied as a liquid in Tris saline 0.5 mg/ml, 0.02% sodium azide, pH 7.3, 0.5% BSA.

May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Small volumes of anti-ABCB10 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined; however, this protein may play a role in lysosomes. Alternative splicing of this gene results in distinct isoforms which are likely to have different substrate specifications.

Antibodies; Abs to Multi Drug Resistance (MDR)

ELISA (EL/EIA)

Suitable for use in ELISA.
Dilution: ELISA: 1:64000

79,148 Da[Similar Products]

ATP-binding cassette, sub-family B (MDR/TAP), member 10

ATP-binding cassette sub-family B member 10, mitochondrial; OTTHUMP00000037475; ABC transporter 10 protein; ATP-binding cassette transporter 10; mitochondrial ATP-binding cassette 2

ATP-binding cassette sub-family B member 10, mitochondrial

ABCBA_HUMAN

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The function of this mitochondrial protein is unknown. [provided by RefSeq]

ABCB10: May mediate critical mitochondrial transport functions related to heme biosynthesis. Belongs to the ABC transporter superfamily. ABCB family. Mitochondrial peptide exporter (TC 3.A.1.212) subfamily.

Protein type: Membrane protein, multi-pass; Hydrolase; Mitochondrial; Transporter; Transporter, ABC family; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q42.13

Cellular Component: mitochondrial inner membrane

Molecular Function: protein homodimerization activity; ATPase activity, coupled to transmembrane movement of substances; transporter activity; ATP binding

Biological Process: metabolic process; transport; transmembrane transport

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