Full Product Name
KCNE3 Antibody
Product Synonym Names
KCNE3; MinK-related peptide 2; HOKPP; HYPP; MiRP2
Product Gene Name
anti-KCNE3 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q9Y6H6
Species Reactivity
Human, Mouse, Rat
Specificity
KCNE3 Antibody detects endogenous levels of total KCNE3
Form/Format
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0mg/mL (lot specific)
Immunogen
A synthesized peptide derived from human KCNE3
Preparation and Storage
Store at -20 degree C
Other Notes
Small volumes of anti-KCNE3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Product Categories/Family for anti-KCNE3 antibody
Total protein Ab
Applications Tested/Suitable for anti-KCNE3 antibody
Western Blot (WB)
Application Notes for anti-KCNE3 antibody
Western Blot: 1:1000-3000
Western Blot (WB) of anti-KCNE3 antibody
Western blot analysis KCNE3 using Jurkat whole cell lysates
NCBI/Uniprot data below describe general gene information for KCNE3. It may not necessarily be applicable to this product.
NCBI Accession #
NP_005463.1
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NCBI GenBank Nucleotide #
NM_005472.4
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UniProt Primary Accession #
Q9Y6H6
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UniProt Related Accession #
Q9Y6H6[Other Products]
Molecular Weight
11,710 Da
NCBI Official Full Name
potassium voltage-gated channel subfamily E member 3
NCBI Official Synonym Full Names
potassium voltage-gated channel subfamily E regulatory subunit 3
NCBI Official Symbol
KCNE3??[Similar Products]
NCBI Official Synonym Symbols
HYPP; HOKPP; MiRP2
??[Similar Products]
NCBI Protein Information
potassium voltage-gated channel subfamily E member 3
UniProt Protein Name
Potassium voltage-gated channel subfamily E member 3
UniProt Synonym Protein Names
MinK-related peptide 2; Minimum potassium ion channel-related peptide 2; Potassium channel subunit beta MiRP2
Protein Family
Potassium voltage-gated channel subfamily
UniProt Gene Name
KCNE3??[Similar Products]
UniProt Entry Name
KCNE3_HUMAN
NCBI Summary for KCNE3
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a type I membrane protein, and a beta subunit that assembles with a potassium channel alpha-subunit to modulate the gating kinetics and enhance stability of the multimeric complex. This gene is prominently expressed in the kidney. A missense mutation in this gene is associated with hypokalemic periodic paralysis. [provided by RefSeq, Jul 2008]
UniProt Comments for KCNE3
KCNE3: Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Belongs to the potassium channel KCNE family.
Protein type: Channel, potassium
Chromosomal Location of Human Ortholog: 11q13.4
Cellular Component: cytoplasm; dendrite; lipid raft; perikaryon; plasma membrane; vesicle; voltage-gated potassium channel complex
Molecular Function: potassium channel regulator activity; protein binding
Disease: Brugada Syndrome 6
Research Articles on KCNE3
1. Based on current evidence from published studies, neither of the two variants from KCNE was significantly associated with the risk of Meniere's disease--{REVIEW}
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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