Full Product Name
KCNE3 Antibody
Product Synonym Names
DKFZp781H21101; HOKPP; MGC102685; MGC129924; MiRP2
Product Gene Name
anti-KCNE3 antibody
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for Q6IAE6
Species Reactivity
Human, Mouse, Rat
Purity/Purification
Antigen affinity purification
Immunogen
Fusion protein of KCNE3
Calculated Molecular Weight: 103aa; 12kd
Buffer
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of anti-KCNE3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Applications Tested/Suitable for anti-KCNE3 antibody
ELISA (EIA)
NCBI/Uniprot data below describe general gene information for KCNE3. It may not necessarily be applicable to this product.
NCBI Accession #
CAG33490.1
[Other Products]
UniProt Primary Accession #
Q6IAE6
[Other Products]
UniProt Related Accession #
Q9Y6H6[Other Products]
Molecular Weight
11,710 Da
NCBI Official Full Name
KCNE3
NCBI Official Synonym Full Names
potassium channel, voltage gated subfamily E regulatory beta subunit 3
NCBI Official Symbol
KCNE3??[Similar Products]
NCBI Official Synonym Symbols
HYPP; HOKPP; MiRP2
??[Similar Products]
NCBI Protein Information
potassium voltage-gated channel subfamily E member 3; cardiac voltage-gated potassium channel accessory subunit; minK-related peptide 2; minimum potassium ion channel-related peptide 2; potassium channel subunit beta MiRP2; potassium voltage-gated channel, Isk-related family, member 3; voltage-gated K+ channel subunit MIRP2
UniProt Protein Name
KCNE3 protein
UniProt Synonym Protein Names
KCNE3 protein
Protein Family
Potassium voltage-gated channel subfamily
UniProt Gene Name
KCNE3??[Similar Products]
UniProt Entry Name
Q6IAE6_HUMAN
NCBI Summary for KCNE3
Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a type I membrane protein, and a beta subunit that assembles with a potassium channel alpha-subunit to modulate the gating kinetics and enhance stability of the multimeric complex. This gene is prominently expressed in the kidney. A missense mutation in this gene is associated with hypokalemic periodic paralysis. [provided by RefSeq, Jul 2008]
UniProt Comments for KCNE3
KCNE3: Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Belongs to the potassium channel KCNE family.
Protein type: Channel, potassium
Chromosomal Location of Human Ortholog: 11q13.4
Cellular Component: voltage-gated potassium channel complex
Molecular Function: voltage-gated potassium channel activity; potassium channel regulator activity
Disease: Brugada Syndrome 6
Research Articles on KCNE3
1. A KCNE3 T4A mutation was identified in a Japanese patient presenting Brugada-pattern ECG and neurally mediated syncope.
Precautions
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Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
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