Product Name
Fc receptor-like protein 2 (FCRL2), Recombinant Protein
Full Product Name
Recombinant Human Fc receptor-like protein 2 (FCRL2), partial
Product Gene Name
FCRL2 recombinant protein
[Similar Products]
Product Synonym Gene Name
FCRL2[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Sequence Positions
20-401. Partial, provide the complete extracellular domain.
Sequence
LTLVAPSSVF EGDSIVLKCQ GEQNWKIQKM AYHKDNKELS VFKKFSDFLI QSAVLSDSGN YFCSTKGQLF LWDKTSNIVK IKVQELFQRP VLTASSFQPI EGGPVSLKCE TRLSPQRLDV QLQFCFFREN QVLGSGWSSS PELQISAVWS EDTGSYWCKA ETVTHRIRKQ SLQSQIHVQR IPISNVSLEI RAPGGQVTEG QKLILLCSVA GGTGNVTFSW YREATGTSMG KKTQRSLSAE LEIPAVKESD AGKYYCRADN GHVPIQSKVV NIPVRIPVSR PVLTLRSPGA QAAVGDLLEL HCEALRGSPP ILYQFYHEDV TLGNSSAPSG GGASFNLSLT AEHSGNYSCE ANNGLGAQCS EAVPVSISGP DGYRRDLMTA GV
3D Structure
ModBase 3D Structure for Q96LA5
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of FCRL2 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Related Product Information for
FCRL2 recombinant protein
This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains one immunoreceptor-tyrosine activation motif and two immunoreceptor-tyrosine inhibitory motifs. This protein may be a prognostic marker for chronic lymphocytic leukemia. Alternatively spliced transcript variants have been described, but their
biological validity has not been determined.
NCBI/Uniprot data below describe general gene information for FCRL2. It may not necessarily be applicable to this product.
NCBI Accession #
NP_001152960.1
[Other Products]
NCBI GenBank Nucleotide #
NM_001159488.1
[Other Products]
UniProt Primary Accession #
Q96LA5
[Other Products]
UniProt Secondary Accession #
Q6NTA1; Q9BZI4; Q9BZI5; Q9BZI6; A0N0M5; A1L307; A6NMS0[Other Products]
UniProt Related Accession #
Q96LA5[Other Products]
Molecular Weight
22,533 Da
NCBI Official Full Name
Fc receptor-like protein 2 isoform 2
NCBI Official Synonym Full Names
Fc receptor like 2
NCBI Official Symbol
FCRL2??[Similar Products]
NCBI Official Synonym Symbols
FCRH2; IFGP4; IRTA4; SPAP1; CD307b; SPAP1A; SPAP1B; SPAP1C
??[Similar Products]
NCBI Protein Information
Fc receptor-like protein 2
UniProt Protein Name
Fc receptor-like protein 2
UniProt Synonym Protein Names
Fc receptor homolog 2; FcRH2; IFGP family protein 4; Immunoglobulin receptor translocation-associated protein 4; SH2 domain-containing phosphatase anchor protein 1; CD_antigen: CD307b
Protein Family
Fc receptor-like protein
UniProt Gene Name
FCRL2??[Similar Products]
UniProt Synonym Gene Names
FCRH2; IFGP4; IRTA4; SPAP1; FcR-like protein 2; FcRL2; FcRH2??[Similar Products]
NCBI Summary for FCRL2
This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains one immunoreceptor-tyrosine activation motif and two immunoreceptor-tyrosine inhibitory motifs. This protein may be a prognostic marker for chronic lymphocytic leukemia. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Apr 2009]
UniProt Comments for FCRL2
May have an regulatory role in normal and neoplastic B cell development.
Research Articles on FCRL2
1. decreased FCRL4 expression and association of FCRL2 expression with inflammatory markers and disease activity suggested the contribution of these molecules to rheumatoid arthritis inflammatory processes.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
