Product Name
Sodium channel protein type 4 subunit alpha (Scn4a), Recombinant Protein
Full Product Name
Recombinant Rat Sodium channel protein type 4 subunit alpha (Scn4a) , partial
Product Gene Name
Scn4a recombinant protein
[Similar Products]
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
3D Structure
ModBase 3D Structure for P15390
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
>85% (SDS-PAGE) (lot specific)
Form/Format
Liquid containing glycerol
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
Species
Rattus norvegicus (Rat)
Storage Buffer
Tris-based buffer, 50% glycerol
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
ISO Certification
Manufactured in an ISO 13485:2003 and EN ISO 13485:2012 Certified Laboratory.
Other Notes
Small volumes of Scn4a recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
NCBI/Uniprot data below describe general gene information for Scn4a. It may not necessarily be applicable to this product.
NCBI Accession #
NP_037310.1
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NCBI GenBank Nucleotide #
NM_013178.1
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UniProt Primary Accession #
P15390
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UniProt Secondary Accession #
O70611[Other Products]
UniProt Related Accession #
P15390[Other Products]
Molecular Weight
208,867 Da
NCBI Official Full Name
sodium channel protein type 4 subunit alpha
NCBI Official Synonym Full Names
sodium voltage-gated channel alpha subunit 4
NCBI Official Symbol
Scn4a??[Similar Products]
NCBI Official Synonym Symbols
NCHVS; Nav1.4; microI
??[Similar Products]
NCBI Protein Information
sodium channel protein type 4 subunit alpha
UniProt Protein Name
Sodium channel protein type 4 subunit alpha
UniProt Synonym Protein Names
Mu-1; SkM1; Sodium channel protein skeletal muscle subunit alpha; Sodium channel protein type IV subunit alpha; Voltage-gated sodium channel subunit alpha Nav1.4
Protein Family
Sodium channel protein
UniProt Gene Name
Scn4a??[Similar Products]
NCBI Summary for Scn4a
voltage-gated Na+ channel subunit [RGD, Feb 2006]
UniProt Comments for Scn4a
This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na+ ions may pass in accordance with their electrochemical gradient. This sodium channel may be present in both denervated and innervated skeletal muscle.
Research Articles on Scn4a
1. the role of the intracellular IFM motif of rNav1.4 (skeletal muscle isoform of the rat Na(+) channel) on the alpha-beta1 functional interaction
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
